Associations between compound heat exposure and cognitive impairment and the potential mediating role of plasma sphingolipid metabolites: Evidence from a large-scale population cohort study.

Long-term exposure to ambient air pollution and lipid profiles: a longitudinal study in a heavily industrialized region of northern China

Background Dyslipidemia is an important modifiable risk factor for cardiovascular disease, and growing evidence suggests that long-term ambient air pollution exposure may adversely affect lipid metabolism. However, longitudinal evidence from heavily industrialized regions with complex multipollutant exposure remains li...

Association between long-term ambient air pollution exposure and cognitive disorders among older adults in China: the mediating role of lifestyle

Air pollution increased the risk of CDs among older adults, which was partially offset by a healthy lifestyle, and lifestyle interventions may help address some challenges inherent in controlling air pollution in ageing societies.

Associations of single and combined exposure to plasma metals with biological aging in Chinese adults: Mediation by inflammation and oxidative stress and moderation by diabetes.

This cross-sectional study examined the single and combined associations of plasma metals with biological aging and explored the potential mediating roles of inflammation and oxidative stress, as well as the modifying effect of diabetes. Seventeen plasma metals and four biological age acceleration metrics (KDM_accel, P...

[Joint effects of heatwave exposure and apolipoprotein E genotype on risk for cognitive impairment in older adults].

Compound Heatwave and Ozone Pollution Events and the Risk of Neurodegenerative Diseases: A 9-Year Electronic Health Records Cohort Study in China

While NDD cases clustered in urban regions (Moran’s I = 0.351), rural communities faced higher predicted risk, highlighting the need for joint climate and air quality governance and targeted community health interventions.

Long-Term Air Pollution Exposure, Cardiovascular Disease, and Cardiometabolic Risk Factors in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study

Long-term exposure to ambient air pollution, particularly particulate matter, is associated with an increased risk of CVD and cardiometabolic disorders in middle-aged and older Chinese adults.