Oct 2026· PLoS ONE· Vol 21· 0 citations· 39 references
Medicine
Abstract
Missing data is a challenging issue in data analysis. Researchers often address the issue by simply removing incomplete cases from the analysis. However, this approach reduces the sample size and can undermine the accuracy of statistical estimates. Alternatively, imputation techniques can be used to replace missing values with plausible estimates, resulting in a more complete dataset and more reliable estimates. In this study, we propose a new imputation method, which we call Layered Stacking. The method is designed to improve the estimation of continuous missing values. To evaluate its effectiveness, comprehensive simulation studies were carried out with four distinct data generating processes using datasets generated under the missing at random mechanism, with sample sizes of 500, 1,000, 5,000 and 10,000, and missingness rates of 10, 20, 30 and 40%. The proposed method is compared with five widely used imputation techniques: k-nearest neighbors, support vector regression, decision tree, random forest and extreme gradient boosting. Evaluation metrics include mean squared imputation error (MSIE) and mean absolute percentage imputation error (MAPIE) along with standard deviation (SD) and 95% confidence interval (CI) across replications. Two real-world datasets have also been considered to assess the performance of the method. The proposed method generally achieved lower MSIE than the benchmark models, particularly for larger datasets.
This work proposes two hybrid imputation methods, which combine nuclear-norm-based low-rank initialization using Singular Value Thresholding and SoftImpute, respectively, with a non-iterative Random Forest refinement, effectively exploits the low-rank structure of real-world tabular data and accommodates mixed-type var...
Jin-Wei Li, Michelle Bruch, Daniel Tenbrinck· 0 citations
Estimating the finite population parameters is primary objective in many studies, especially
when some units fail to respond. These units are known as missing values for specific
variables. Some important reasons for missing data may be due to incomplete data entry by
the surveyor, broken equipment, misplaced observati...
D. Bhattacharyya, A. K. Pandey, Sohaib Ahmad· Boletim da Sociedade Paranae...· 0 citations
Choosing an appropriate imputation strategy for clinical datasets requires understanding which missing data mechanism is operative, yet most imputation benchmarks conflate performance across mechanisms. The present work addresses this gap by conducting the first mechanism-stratified comparison of three imputation appro...
Kurban Kotan, Serdar Kırışoğlu· PLoS ONE· 0 citations
For model comparison in random effects probit models with incompletely observed covariates, this paper develops a Bayesian data-augmentation workflow in which latent Gaussian responses, random effects, and missing covariate values are updated within a common augmented sampling scheme. Because specifying a fully param...
Michael Bergrab· Statistical Methods & Ap...· 0 citations
The fast growth of high-dimensional datasets in computational biology, industrial IoT, and socio-economic research has made the issue of missing data more challenging. This common problem reduces statistical power and introduces systematic bias in later machine learning tasks. Traditional methods, such as listwise dele...
Mahmoud M. Ismail, M. Emad, Mai Mohamed· Scientific Reports· 0 citations
Missing covariates are frequently encountered in supervised learning problems, and classical methods for estimation using such data use carefully chosen imputation schemes for missing data, or likelihood approximations that lead to nonconvex $M$-estimation problems. These methods and their relatives are suitable for sc...
Jyotishka Ray Choudhury, K. A. Verchand, R. Samworth et al.· 0 citations
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