Skip to content
#explainable ai Review Open access

A Comprehensive Study of Machine Learning and Deep Learning for Heart Disease Prediction

Sep 2026 · Applied and Computational Engineering · 0 citations
Artificial Intelligence in Healthcare

TL;DR

The problems of this paper are the problems of this paper, and some future directions for constructing a reliable cardiac disease prediction system with clinical applications are proposed.

Abstract

Cardiovascular diseases are the main reasons for death around the world at present, so early detection and intervention can be difficult. Review of Recent Applications of Machine Learning and Deep Learning in Cardiovascular Disease Prediction. Logistic regression, decision trees, random forests, support vector machines and gradient boosting have all been applied to the Cleveland and Kaggle cardiovascular datasets in previous studies. Based on research results, soft voting and stacking ensemble methods have been used to improve the prediction accuracy of a single classifier. Dense neural networks and hybrid Convolutional Neural Network - Long Short-Term Memory (CNN-LSTM) architectures are also deep learning models that have been researched and applied. Add to the above that SHapley Additive exPlanations (SHAP) and Local Interpretable Model-agnostic Explanations (LIME) are popular methods for explaining Artificial Intelligence (AI) models. However, there are still many problems, such as an abundance of small public datasets, class imbalance, a lack of external validation, and poor clinical interpretability. The above are the problems of this paper, and some future directions for constructing a reliable cardiac disease prediction system with clinical applications are proposed.

Read PDF

Similar papers

Open access Aug 2026

An Advanced Ensemble Framework for Robust Heart Disease Detection and Classification

A robust Ensemble Learning (EL) framework for the prediction and classification of CVD by integrating multiple ML algorithms with a DL component using an Artificial Neural Network employed as a feature extraction layer prior to ensemble aggregation is presented.

El Haddad Khadija, A. Bekkari, W. Bouarifi et al. · 0 citations
Open access 2026

Comparative performance of machine learning and deep learning models for heart disease prediction in a small clinical dataset.

BACKGROUND Machine learning (ML) and deep learning (DL) models are increasingly applied to cardiovascular risk prediction, yet their comparative performance in small tabular clinical datasets remains uncertain. This study compared conventional machine learning models and a deep neural network for predicting angiographi...

Erfan Barootchi, Pardis Zamani, R. Birgani et al. · 0 citations
Open access Aug 2026

A Deep Learning-Based Predictive Framework for Early Heart Disease Risk Assessment Using Multi-Factor Clinical Data

CardioAttentionNet is proposed, a novel hybrid deep learning framework that integrates residual convolutional neural networks, transformer encoders with multi-head self-attention, bidirectional long short-term memory networks, and cross-attention modules for comprehensive cardiovascular risk prediction.

Swapnil Hiralal Chaudhari, A. K. Choudhary · 0 citations
Review Open access Aug 2026

Comprehensive machine learning approaches for disease prediction current applications recent advances and future prospects

The reviewed studies demonstrated that Deep learning approaches, particularly convolutional neural networks, transformer-based models, and multimodal frameworks, showed improved predictive accuracy when large and diverse datasets were available.

Tehreem Khan, Tayyaba Usman, Ifrah Khalid et al. · 0 citations
Review Open access Aug 2026

Artificial Intelligence for Early Heart Disease Prediction: A Review of Machine Learning Techniques

There is an urgent need for explainable, clinically validated and standardised ML frameworks to translate predictive models into routine healthcare practice and improve early detection of cardiovascular disease.

Hanna Rasheed, Arya.K.R Arya.K.R, Ashida.K.A Ashida.K.A · 0 citations
Sep 2026

Ensemble and Explainable AI-Based Framework for Early Prediction of Heart Disease

The proposed hybrid and explainable machine learning architecture demonstrates substantial predictive accuracy, robustness, and interpretability for the early detection of heart disease.

Sudipta Bhattacharya, Bingshati Mondal, Nabanita Das et al. · 0 citations

Related blog posts

MIT News · Artificial Intelligence Oct 15, 2026

AI model decodes the language cells use to communicate

A new computational approach reveals how cells communicate to assemble into tissues. This could accelerate stem cell engineering, improve disease models, and inform therapies.

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.