Oct 2026· Інфокомунікаційні та комп'ютерні технології· pp. 248· 0 citations· 9 references
TL;DR
A five-level taxonomy of large language model interpretation methods is proposed, covering the range from the analysis of individual neuron activations to behavioral testing at the level of complete textual outputs, and it is demonstrated that proper probability calibration is a necessary prerequisite for the practical application of interpretation and verification results.
Abstract
The rapid evolution and adoption of large language models in domains with a high cost of error, including healthcare, law, finance, and education, where incorrect or factually inaccurate responses may lead to erroneous decisions, necessitate the study of the theoretical and practical aspects of the interpretation, calibration, evaluation, and verification of large language model outputs.This article systematizes contemporary approaches to the interpretation and verification of large language model decisions and identifies the roles of trust metrics in constructing protocols for assessing their reliability. The study analyzes methods of mechanistic interpretability, including sparse autoencoders and computational circuit tracing, approaches to chain-of-thought analysis, calibration metrics such as Expected Calibration Error (ECE) and Brier score, semantic entropy, verbalized confidence, and conformal prediction. Particular attention is devoted to the standardized evaluation frameworks HELM and LM Evaluation Harness, the LLM-as-a-judge paradigm, as well as factuality assessment methods including FActScore, SAFE, and SelfCheckGPT. Based on the conducted analysis, a five-level taxonomy of large language model interpretation methods is proposed, covering the range from the analysis of individual neuron activations to behavioral testing at the level of complete textual outputs. Trust metrics are grouped according to their level of practical maturity, while factuality verification approaches are compared in terms of verification granularity, dependence on external knowledge sources, and computational cost. It is demonstrated that proper probability calibration is a necessary prerequisite for the practical application of interpretation and verification results. Future research should focus on the development of comprehensive evaluation protocols covering the entire lifecycle of a large language model – from training to deployment in production systems.
In this single-centre proof-of-concept, aggregate accuracy was insufficient for safety characterisation: models with indistinguishable mean accuracy carried different catastrophic-failure tiers and reproducibility profiles.
Fang-Yan Liu, Zhi Liu, Xiaolu Fei et al.· Journal of medical systems· 0 citations
This article aims to provide a pragmatic basis for designing and executing rigorous evaluations of healthcare LLMs by describing underlying concepts and potential pitfalls, while emphasizing the importance of aligning evaluation methods with the research question.
S. E. McKinney, P. Vu, S. Justice et al.· 0 citations
Background: Large language model (LLM)–based tools are increasingly used to automate risk-of-bias assessment of randomized controlled trials with the revised Cochrane tool (RoB 2.0). However, their reproducibility, their accuracy, and their fidelity to the deterministic algorithm mapping signalling-question responses t...
Jiae Choi, Heather Swan, Min Jung Kim et al.· Journal of Evidence-Based Pr...· 0 citations
It is shown that current large language models generally perform poorly on most of the safety tests, regardless of their safety alignment mechanisms, which underscores the crucial need for ongoing human oversight and the implementation of strict safety guardrails before deploying these tools in clinical practice.
Yi-Fan Yang, Qiao Jin, Robert Leaman et al.· Communications Medicine· 0 citations
A general framework with equations to balance cost-benefit trade-offs when engineering LLM-based systems for medical reasoning and QA is formulated and generalizable configurations, designs, and patterns are recommended to achieve accuracy and efficiency objectives.
Kiran Bhattacharyya, S. Kamabattula· PLOS Digital Health· 0 citations
Increasing adoption of language models in sensitive sectors such as healthcare,
finance, cybersecurity, education, etc., highlights the significance of developing
transparent decision support systems. This paper reviews the use of explanation
techniques for language and machine learning models, including SHAP, LIME,
at...
Mary Shakkina C, Miranda Lakshmi Travis· International Journal of Mod...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.