TL;DR
Omega-7 offered prophylactic anti-inflammatory benefit against Dox-induced hepatic injury in albino rats, confirmed by histological and biochemical findings.
Objective. Omega-7 fatty acids have offered promising hepatoprotective properties in various experimental models. This study aimed to investigate the prophylactic potential of omega-7 supplementation against doxorubicin (Dox)-induced hepatic injury in albino rats. Methods. A total of 42 rats were divided into 6 groups...
BACKGROUND Doxorubicin (DOX) is an effective antineoplastic agent whose clinical use is limited by hepatotoxicity. This study evaluated the hepatoprotective effects of Olea europaea leaf extract (OLE) in a rat model of DOX -induced hepatotoxicity. METHODS Thirty-two male Wistar rats were randomly assigned to four gro...
This study aimed to evaluation the ameliorative, antioxidant, anti-inflammatory, and chemical detoxifying properties of Ephedra alata extract (EAE) in relation to bifenthrin-induced liver damage. Adult male rats (180-220 g) were divided into four groups (10 rats per group) and underwent oral therapy for a duration of 3...
Curcumin showed hepatoprotective effects against H₂O₂-induced oxidative liver injury through antioxidant, anti-inflammatory, anti-proliferative, and anti-apoptotic mechanisms, with the strongest overall protection was observed at 200 mg/kg.
OBJECTIVE Doxorubicin (DOX), a widely used anthracycline chemotherapy drug, has the potential to cause toxicity in multiple organs, particularly the myocardium. This study examines the cardioprotective effects of Syzygium aromaticum L. extract (SAE) in DOX-induced cardiotoxicity. METHODS This study involved 48 male W...
Background: Diabetes mellitus is associated with chronic hyperglycemia that induces oxidative stress and inflammatory responses, leading to progressive hepatic and renal dysfunction. Natural products rich in bioactive compounds, such as date seeds (Phoenix dactylifera), have gained increasing attention for their poten...
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