Aug 2026· Advances in Medical Education and Practice· Vol 17, pp. 1-14· 0 citations· 31 references
Medicine
TL;DR
Assessing LLM-generated assessment items provides valuable insight into the quality of LLM-supported MCQ questions, and there is no significant difference in mean scores and ranks among the three LLMs across different quality criteria.
Abstract
Background The increasing number of student cohorts has compelled academics to create a larger number of Multiple-Choice Question (MCQ) items. Large language models (LLMs) can help educators generate assessment items across multiple disciplines. The study compared the ability of LLMs (Gemini Advanced, Perplexity Pro, and ChatGPT 4.0) to generate high-quality, clinical-scenario-based MCQ items across three disciplines in a medical program, using an 8-point quality rubric. Materials and Methods Learning Outcomes (LOs) from Anatomy and Pathology disciplines of a pre-clinical semester 4 module and Family Medicine discipline of a clinical semester 6 module of a medical undergraduate program were selected. Using a pre-determined descriptive prompt, 63 MCQ items were generated from three AI tools. The quality of item construction was assessed by external content experts who were blinded to item generation using an 8-criterion rubric and a 4-point Likert scale. Mean scores and ranks for MCQs under each LLM were analysed, and a Friedman test was conducted to compare them. Kendall’s W showed that all criteria except one demonstrated some effect and weak-to-fair inter-rater reliability. Results When measuring key problem-solving skills, Perplexity Pro-generated MCQ items received a higher percentage of “strongly agree” ratings in Anatomy (57.1%, n=63), Pathology (56.5%, n=63), and Family Medicine (71.4%, n=63). Perplexity Pro received a higher percentage of “strongly agree” ratings in Anatomy, at 47.6% (n = 63), when evaluating specific content. Gemini Advanced also scored highly, with 68.8% in Pathology and 81% in Family Medicine (n = 63). A comparative analysis of the higher mean scores and ranks across 24 quality criteria showed that Perplexity Pro, Gemini Advanced, and ChatGPT 4.0 achieved 13, 10, and 1 higher mean scores, respectively. There is no significant difference in mean scores and ranks among the three LLMs across different quality criteria. Conclusion MCQs created by Perplexity Pro and Gemini Advanced achieved comparatively higher percentages of “strongly agree” ratings across quality criteria for item construction. Assessing LLM-generated assessment items provides valuable insight into the quality of LLM-supported MCQ questions.
This study provides a benchmark of LLM performance for radiology OSCE-style content generation and evaluation during a specific snapshot of artificial intelligence development (August 2024).
Ankush Ankush, Samriddhi Burman, Sydney Smith et al.· Radiology Advances· 0 citations
Background Large language models (LLMs) perform well on knowledge-based medical examinations, but evidence on their utility for performance-based assessments such as Objective Structured Clinical Examinations (OSCEs) remains limited. Beyond simulating candidate answers, LLMs could support quality assurance of OSCE stat...
É. Lupon, Alexandre O Gérard, Alexandre Destere et al.· Advances in Medical Educatio...· 0 citations
These findings support the use of LLM-generated hospital courses as starting drafts when paired with clinician review and institutional safeguards, and errors were common, but perceived potential harm was low, even assuming use without clinician correction.
Jasmine E. Kim, J. Hron, Daniel J. Kats et al.· Hospital Pediatrics· 0 citations
Some LLMs, particularly ChatGPT and Kimi, showed moderate alignment with human examiners, but the alignemnet was not consistently stable across repeated sessions or operational settings.
Asgeir Brevik, H. Jerpseth, S. Lafontan· Frontiers in Education· 0 citations
The ability of three advanced LLMs to generate pharmacology assessment questions for Phase II MBBS students was examined and the clinical relevance of questions was strong, and human reviewers identified minor factual inaccuracies.
Gurusamy Sivagnanam, Parasuraman Jayabharathy, Ganesan Justina Princess· The Journal of medical resea...· 0 citations
How well large language models (LLM) handle Turkish melanoma patient education varies widely from one model to the next, and findings suggest that LLM-generated Turkish melanoma materials may be useful as preliminary educational drafts.
Nıyazı Çetın, A. Atılan· European Journal of Therapeu...· 0 citations
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