Real-World Evidence of Disproportionate Financial Toxicity and Health-Related Social Needs Among Adolescents and Young Adults Receiving Care at an NCI-Designated Cancer Center
Aug 2026· Current Oncology· Vol 33, pp. 477· 0 citations· 32 references
Medicine
TL;DR
These findings identify AYAs as a high-risk group for financial toxicity and health-related social needs, supporting the development of targeted interventions, policy changes to reduce economic barriers to care, and future research on tailored support programs for adolescent and young adult cancer patients.
Abstract
Simple Summary Adolescents and young adults (AYAs, ages 15–39) with cancer face distinct financial challenges—limited savings, unstable jobs, and insurance gaps—that increase their risk of financial distress and unmet health-related social needs. Using routine electronic screening and billing data from 81,731 patients (5655 AYAs), this study found AYAs were significantly more likely than older or younger patients to report medium/high financial strain, carry unpaid medical debt, and need pre-visit financial review due to unpaid bills; those aged 26–32 showed the highest burden of financial risk, unresolved balances, collection referrals or write-offs, and food insecurity. These findings identify AYAs as a high-risk group for financial toxicity and health-related social needs, supporting the development of targeted interventions, policy changes to reduce economic barriers to care, and future research on tailored support programs for adolescent and young adult cancer patients.
Abstract Financial toxicity represents a major driver of healthcare inequities among oncology patients in low- and middle-income countries (LMICs). This systematic review found that high out-of-pocket healthcare expenditure frequently resulted in catastrophic financial burden, with prevalence estimates ranging from 48....
Makhliyokhon Kuldasheva, Kalash Dwivedi, Nilufar T. Khamzayeva et al.· Indian Journal of Medical an...· 0 citations
INTRODUCTION
Research suggests that medical debt and difficulty paying medical bills are associated with worse mental health. However, limited research examines the longitudinal association between medical spending as a proportion of income and later mental health.
METHODS
Using a series of two-year panels from the U...
Michael Caniglia, Laura Chavez· American Journal of Preventi...· 0 citations
Background: Cervical cancer is a major health challenge in low-and middle-income countries (LMICs), where households face high out-of-pocket costs and limited financial risk protection (FRP). Insufficient FRP for treatment leads to catastrophic health expenditure (CHE), impoverishing health expenditure (IHE) and distre...
Denis Okova, Jennifer Moodley, Patricia Makwambeni et al.· ecancermedicalscience· 0 citations
Financial toxicity (the financial burden that accompanies a cancer diagnosis) uniquely affects adolescent/young adult cancer survivors (AYACS). The objective of this study was to use a mixed-method approach to understand AYACS’ perspectives on financial consequences of cancer treatment, to complement quantitative measu...
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Robina Josiah Willock, D. Parks, Samah Nabi et al.· Journal of cancer survivorsh...· 0 citations
The prevalence and financial burden of non-communicable diseases (NCDs) are increasing worldwide. While evidence from many studies indicated that households with NCD members are at greater financial risk, little information is available in Vietnam. Therefore, this study was conducted to examine the magnitude of financi...
Linh Thi Mai Nguyen· 0 citations
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