Prevalence of Newly Diagnosed Diabetes Mellitus in Acute Stroke Patients A Multicenter Cross-Sectional Study
TL;DR
Routine screening for DM using HbA1c should be considered for all acute stroke patients without known diabetes, as newly diagnosed DM is highly prevalent among acute stroke patients in this setting and is associated with poor outcomes.
Abstract
Background: Diabetes mellitus (DM) is a well-established risk factor for stroke, but the prevalence of newly diagnosed DM among acute stroke patients in Ethiopia is not well characterized. Objective: To determine the prevalence of newly diagnosed DM and its associated factors among acute stroke patients at Tikur Anbessa Specialized Hospital and Yekatit 12 Hospital Medical College. Method: A multicenter retrospective cross-sectional study was conducted among 182 acute stroke patients without prior DM diagnosis. Data were collected from medical records (October 2019–September 2021). Newly diagnosed DM was defined as fasting blood glucose ≥126 mg/dL and/or HbA1c ≥6.5%. Results: The prevalence of newly diagnosed DM was 11.5% (21/182). An additional 15.9% (29/182) had prediabetes. Independent risk factors included male sex (AOR=2.87, 95% CI: 1.10–7.50), smoking (AOR=7.72, 95% CI: 2.93–20.37), alcohol use (AOR=5.89, 95% CI: 2.15–16.08), and family history of DM (AOR=12.23, 95% CI: 3.45–43.35). Mortality was significantly higher among newly diagnosed DM patients (85.7%) compared to non-diabetics (P<0.001). Conclusion: Newly diagnosed DM is highly prevalent among acute stroke patients in this setting and is associated with poor outcomes. Routine screening for DM using HbA1c should be considered for all acute stroke patients without known diabetes