The potential of EHT as an effective and eco-friendly molluscicide for the control of O. hupensis is suggested, which is one of the most rapid and effective strategies for disrupting schistosomiasis transmission.
Abstract
The snail, Oncomelania hupensis, is the only intermediate host of Schistosoma japonicum. Thus, snail control is one of the most rapid and effective strategies for disrupting schistosomiasis transmission. In this study, 125 botanical extracts were screened for molluscicidal activity, leading to the selection of the extract of Helleborus thibetanus (EHT) for further evaluation. EHT exhibited strong molluscicidal activity against O. hupensis (LC50 value of 12.54 mg/L and LD50 value of 1.400 g/m2). In field trials, an EHT dose of 10 g/m2 killed 85.19% of the snails. Histopathological evaluation revealed that EHT caused comprehensive damage to the cephalopodium, gill, salivary gland, stomach, and hepatopancreas. Importantly, EHT was also generally safe for non-target organisms, such as Danio rerio, Daphnia magna, Pelophylax nigromaculatus, Cipangopaludina chinensis, and Neocaridina denticulata at the test concentration. These results suggest the potential of EHT as an effective and eco-friendly molluscicide for the control of O. hupensis.
Findings support the hypothesis that M. urundeuva may act through a multi-target mechanism by potentially affecting neuromuscular and metabolic homeostasis, reinforcing the interest in EE as a potential candidate for integrated R. microplus management.
Viviane de Oliveira Vasconcelos, Marta Cristina Pereira da Silva, Eduarda Victória Alves Paulino de Azevedo et al.· Experimental parasitology· 0 citations
The increasing development of acaricide resistance in Rhipicephalus microplus has created a need for alternative and environmentally sustainable approaches to tick control. Plant-derived products containing bioactive compounds may provide useful botanical alternatives to conventional acaricides. The present study evalu...
P. Jumade, K. Kharkar, Alka R. Sawarkar et al.· IOASD Journal of Medical and...· 0 citations
The golden apple snail (Pomacea canaliculata) remains one of the most damaging pests of rice in the Philippines, feeding on young seedlings and cutting yields. This study examined whether ethanolic leaf extracts of Averrhoa bilimbi (kamias) and Cardiospermum halicacabum (balloon vine), applied alone and in combination,...
Jazzie Anne I. Abuid, Brennda Cruz, Maria Georgina S. Dazon et al.· International Journal of Res...· 0 citations
Abstract The mollusk Achatina fulica, commonly known as the giant African snail, is a terrestrial gastropod native to East Africa that is spreading worldwide because of its high adaptability and reproductive capacity. This invasive species causes agricultural damage, negatively affects biodiversity, and poses risks to...
M. R. E. Silva, C. F. Pereira, K. N. F. Gomes et al.· Brazilian Journal of Biology· 0 citations
Schistosomiasis is a millennium-old disease that affects approximately 235 million people. Considering that most of the population affected by schistosomiasis faces varying levels of poverty, finding plant-derived compounds that can help control or eradicate this disease would be worthwhile, especially if the plants ar...
Deborah Bortolucci Hartmann, Renan Alberto Marim, G. Zardeto et al.· Brazilian Journal of Animal...· 0 citations
Evaluating the effect of silver bionanoparticles (AgNPs) on the emergence, feeding, and morphometry of T. radiata highlighted the potential of AgNPs as a safe alternative in pest management, promoting the conservation of natural enemies; however, it is suggested to evaluate AgNPs in sublethal doses to determine their c...
Vidal Zavala-Zapata, Maricarmen Sánchez-Borja, Sonia N. Ramírez-Barrón et al.· Journal of entomological sci...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
