Estimating the average treatment effect (ATE) remains a fundamental challenge in observational studies in the presence of poor or limited covariate overlap. Although the inverse probability weighting (IPW) estimator is a widely used approach for estimating the ATE, its performance can deteriorate substantially when overlap is limited, often resulting in increased finite sample bias and unreliable confidence intervals. One common strategy is to shift attention from the original target estimand, the ATE, to alternative estimands such as a class of weighted ATEs that are less sensitive to extreme propensity scores; however, doing so changes the scientific question of interest. In this manuscript, we propose a novel ATE estimator that preserves the original target estimand, the ATE, while improving robustness to limited overlap. A key idea is that this class of estimands can be represented by a polynomial function of a hyperparameter characterizing the estimands. Exploiting this structure, the proposed method computes IPW estimators for a sequence of such estimands, models these estimates using a polynomial regression, and extrapolates to recover the ATE. We show that the estimator has consistency and asymptotic normality under weaker overlap conditions than required for the standard IPW estimator. Simulation studies demonstrate that the proposed method improves estimation accuracy and interval performance in settings with limited overlap. In addition to its theoretical and empirical advantages, the proposed approach has a clear interpretation and is easy to implement using standard statistical software.
In many scientific studies, evaluating the association between two responses requires adjusting for shared covariates. The expected conditional covariance measures this adjusted association and is used in conditional independence testing and treatment effect estimation. Researchers often estimate it using fitted condit...
Model averaging emerges as an attractive ensemble technique that strategically synthesizes all available information from potential candidate models to enhance estimation accuracy. Despite of having been widely practiced in various areas in biostatistics and economics, its application to causal inference is rather limi...
Studying heterogeneous treatment effects has become essential in experimental and observational studies. A critical assumption for obtaining reliable treatment effect estimates is overlap, which requires that treated and control units have sufficiently similar covariate distributions. Poor overlap may limit the effecti...
Randomized controlled trials (RCTs) identify treatment effects without confounding but are often small, whereas observational studies (OBS) are large but may be confounded. Many estimators combining a small RCT with a large OBS have been developed for the average treatment effect (ATE) and the conditional ATE (CATE). H...
Imputation-based causal estimation is typically viewed as relying exclusively on an outcome model, in contrast to augmented inverse-probability weighting, whose consistency is protected by fitting two nuisance models. This paper argues that this view can be misleading by highlighting a hidden dual weighting structure i...
In observational studies, the overlap assumption, also called positivity, is frequently strained in practice. Limited overlap destabilizes widely used estimators such as inverse propensity weighting (IPW), whose variance depends on density ratios that explode as propensity scores approach zero or one. To address this c...
Yi-Dan Xu, Yi-Xing Wang, X. Nguyen· 0 citations
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