[Effects and mechanisms of Abelmoschus manihot-derived extracellular vesicle-like particles in inhibiting podocyte oxeiptosis in diabetic kidney disease by targeted regulation of "mitochondria-endoplasmic reticulum coupling"].

Yu Wang Yan-Ru Huang Yi-Gang Wan Han-Bing Zhao Shi-Yu Shen Liu-Yin Du Hui Wang Tian-Qing Sang Qi-Han He Qi-Jun Fang Wei Wu F. Chong

Sep 2026 · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · Vol 51 18, pp. 5117-5130 · 0 citations

Medicine

TL;DR

The in vivo and in vitro effects in vivo and in vitro of AM-EVLPs in protecting against podocyte injury using a modified rat model with diabetic kidney disease and a high-glucose(HG)-induced podocyte model showed that the ameliorative effect of H-AM-EVLPs was superior to that of TFA.

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