Skip to content

Real-World Analysis of Neoadjuvant Immunochemotherapy Followed by Surgery in Esophageal Cancer with Baseline Supraclavicular Lymph Node Involvement.

Sep 2026 · Annals of Surgical Oncology · 0 citations · 41 references
Medicine

TL;DR

Although PORT did not significantly improve survival in the overall cSCLN+ population, a trend toward improved OS was observed in the cSCLN+pSCLN+ subgroup, suggesting PORT may be considered as a potential strategy to improve survival outcomes.

View source

Similar papers

Oct 2026

Superior Prognosis of Neoadjuvant Immunochemotherapy over Neoadjuvant Chemoradiotherapy in Esophageal Squamous Cell Carcinoma Patients with pCR.

BACKGROUND Neoadjuvant chemoradiotherapy (NCRT) is the standard regimen for locally advanced esophageal squamous cell carcinoma (ESCC), while neoadjuvant immunochemotherapy (NICT) has emerged as a promising alternative. Achieving pathological complete response (pCR) after neoadjuvant therapy is associated with favorabl...

Pin-Hao Fang, Xin Xiao, Cheng-Yi Mao et al. · 0 citations
Open access Oct 2026

Definitive radiotherapy versus surgery after neoadjuvant immunochemotherapy for locally advanced esophageal squamous cell carcinoma: a propensity score-matched study of efficacy and safety

Comparing the survival outcomes and recurrence patterns of radical surgery and definitive radiotherapy following NICT in patients with LA-ESCC concluded that Definitive RT may be an organ-preserving option in selected patients, especially those with upper esophageal cancer or a favorable response to NICT.

Qiu-Ying An, Ya-Ge Jia, Meng-Lu Liu et al. · 0 citations
Open access Oct 2026

Comparison of neoadjuvant treatment strategies in resectable locally advanced esophageal squamous cell carcinoma: A real-world study

The optimal neoadjuvant regimen for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains uncertain, and pretreatment indicators are lacking. To evaluate and compare the efficacy and safety of three major neoadjuvant strategies in current clinical practice for patients with resecta...

Xiao-Han Wang, Jing-Jing Liu, Jie Cui et al. · 0 citations
Sep 2026

The role of adjuvant therapy in non-pCR patients after neoadjuvant chemoimmunotherapy: Comparison with neoadjuvant chemoradiotherapy for ESCC.

BACKGROUND Neoadjuvant chemoimmunotherapy (NCIT) is increasingly used for locally advanced esophageal squamous cell carcinoma (ESCC), but the role of adjuvant therapy-particularly immunotherapy-after NCIT remains undefined. METHODS This single-institution retrospective study included 458 ESCC patients treated with ne...

Yu-Hao Peng, Xin Xiao, Pin-Hao Fang et al. · 0 citations
Open access Sep 2026

Comparative outcomes of neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in locally advanced thoracic esophageal squamous cell carcinoma: a target trial emulation

Background Neoadjuvant chemoradiotherapy (NCRT) is standard for locally advanced esophageal squamous cell carcinoma (ESCC), while neoadjuvant immune-chemotherapy (NICT) is a promising alternative. This study compared pathological response and long-term survival between NICT and NCRT followed by surgery using a target t...

Zhi-Yu Li, Qiu-Xi Zhou, Qin Xie et al. · 1 citation
Open access Oct 2026

Role of postoperative radiotherapy in locally advanced esophageal squamous cell carcinoma after neoadjuvant chemoimmunotherapy: A retrospective propensity score-matched study

Although neoadjuvant immunochemotherapy (NCIT) has shown promising prospects in the treatment of locally advanced esophageal squamous cell carcinoma (LA-ESCC), the role of adjuvant radiotherapy in these patients remains unclear. This study aimed to investigate the impact of postoperative adjuvant radiotherap...

Li Li, X. Jing, Ming-Juan Sun et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.