Oct 2026· Probiotics and Antimicrobial Proteins· 0 citations· 60 references
Medicine
TL;DR
A comprehensive literature search was conducted across PubMed, Scopus, Web of Science, and Google Scholar without time restrictions using standardized keywords related to gut microbiota, extracellular vesicles, and cancer.
This review consolidates current knowledge of MEV origins across kingdom boundaries, diverse biogenesis routes and conserved biology from prokaryotes to eukaryotes, along with the mechanistic pathways governing MEV uptake by host cells, to highlight the dualistic nature of MEVs.
D. Govindarajan, Viktoria Hentschel, T. Seufferlein· Trillium Extracellular Vesic...· 0 citations
Gut microbiota-derived extracellular vesicles (EVs) have emerged as important mediators of host-microbiota communication, influencing physiological and pathological processes across multiple organ systems through gut-organ axes. These nanoscale vesicles can exert either protective or pathogenic effects depending on the...
Zhi-Rong Rao, Lin-Wei Li, Ying Liang et al.· Clinical and Translational G...· 0 citations
Cancer remains a major global health challenge, and growing evidence indicates that the gut microbiota plays an important role in cancer initiation, progression, metastasis, and response to treatment through complex interactions with host signaling, metabolism, and immunity. This comprehensive narrative review discusse...
P. Negi, Arpita Upreti, Preeti Budhlakoti et al.· Frontiers in Molecular Biosc...· 0 citations
This review synthesizes evidence linking the bacteriome, mycobiome, and phageome to colorectal carcinogenesis, immune modulation, metabolic signaling, and therapeutic response and proposes that therapeutic resistance may sometimes reflect a treatment-selected ecological state rather than the action of a single resistan...
Shamim Pourbahrighesmat, Alireza Tojjari, G. Laliotis et al.· Frontiers in Physiology· 0 citations
Cancers develop within a host ecosystem in which kinds of factors such as gut and tumor‐resident microbiota influence the tumor microenvironment (TME) and therapeutic response. High‐throughput sequencing has revealed the presence of low‐biomass bacteria, fungi, and viruses across diverse malignancies, establishing the...
Juan Lu, Meng-Juan Xuan, Liang Yu et al.· MedComm· 0 citations
This systematic review provides a comprehensive overview of available GoC technology used in host–microbe research, including their structural and cellular components, highlighting the potential of GoC models to support biotic characterization and preclinical evaluation while underscoring the need for further validatio...
Jennifer Redondo, Guillermo García-Lainez, Verónica Martínez-Ríos et al.· Microorganisms· 0 citations
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