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TL;DR
Young age at diagnosis of focal epilepsy, diagnosis of cortical dysplasia, MTS, and presence of complex partial seizures are risk factors for drug-resistant epilepsy.
OBJECTIVE Drug-resistant epilepsy (DRE) is associated with increased injury risk, cognitive decline, psychiatric illness, and premature death. Epilepsy surgery can be curative among well-selected individuals but remains underutilized. This study sought to identify people living with DRE in electronic health record (EHR...
Among patients with acute-phase AE and seizures, the number of ASMs at discharge and the absence of prodromal infection symptom are probable clinical indicators for predicting AEAE, which may facilitate early risk stratification and optimize management strategies for patients with AE-related seizures.
Age significantly reduces the diagnostic yield of rEEG in CAE and JAE, regardless of ASM treatment, and Youden's exploratory analysis identified ≥ 14 years as the optimal threshold for predicting a rEEG negative.
OBJECTIVES Distinguishing Idiopathic Generalized Epilepsy (IGE) from focal epilepsy (FE) can be challenging when IGE cases present with asymmetric clinical or electroencephalographic (i.e., atypical) features. We aimed to identify factors that lead to discordance in IGE diagnoses among epileptologists. METHODS 41 pat...
Overall, the presence of SCSs alone was not associated with a poor outcome, but the spatial non-concordance with the seizure-onset zone was highly predictive for poor seizure outcome.
Patients who report a history of previous medical conditions, particularly those with problematic alcohol/substance use are potentially important risk groups and warrant further examination.
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