Association Between Atherogenic Index of Plasma and Disease Activity in Ankylosing Spondylitis

Abstract

Purpose: Ankylosing spondylitis (AS) is a chronic immune-mediated inflammatory disease associated with increased cardiometabolic risk. The atherogenic index of plasma (AIP), calculated as log₁₀(triglyceride/high-density lipoprotein cholesterol), reflects atherogenic dyslipidemia. This study investigated the association between AIP and disease activity, assessed by the Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP), in patients with AS.Methods: In this retrospective cross-sectional study, consecutive adult patients with AS and lipid profile and ASDAS-CRP data were included. Patients were classified as having low (ASDAS-CRP