Open access
Cytomegalovirus Viremia Is Strongly Associated With 6-Month Mortality Among Adults Living With Advanced HIV Disease: A Prospective Cohort Study in South Africa
Jayne Ellis
Nelesh P. Govender
Nei-Yuan Hsiao
T. Omar
C. Nel
A. H. Mazanderani
C. Tiemessen
Thomas S. Harrison
Joseph N. Jarvis
Rachel M. Wake
Medicine
Abstract
Abstract Cytomegalovirus viremia was detected in 59% (86/146) of adults with very advanced human immunodeficiency virus (HIV) disease (CD4 < 100 cells/µL) attending care in South Africa and was strongly associated with increased 6-month mortality after adjustment for CD4 count and antiretroviral therapy (adjusted odds ratio 4.02, 95% CI 1.27–12.7).