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Review Open access

Dapagliflozin and empagliflozin versus placebo for cardiovascular death or worsening heart failure across the ejection-fraction spectrum: a systematic review and meta-analysis of randomized placebo-controlled trials

Oct 2026 · International Journal of Drug Delivery Technology · 0 citations · 28 references

Abstract

Background and aims: Dapagliflozin and empagliflozin are established therapy for chronic heart failure across the ejection-fraction spectrum. Their pivotal trials were powered for a composite of cardiovascular death and worsening heart failure

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