Review
Open access
Dapagliflozin and empagliflozin versus placebo for cardiovascular death or worsening heart failure across the ejection-fraction spectrum: a systematic review and meta-analysis of randomized placebo-controlled trials
Nawaf AM Alharbi
Abdullah Ahmed Alfllaj
Mohamed Ghaith
Al Abdin
Lana Musaad Alhatlani
I. Fathi
Ibrahim Suliman
Nawaf AM Alharbi
Al Abdin
Lana Musaad Alhatlani
Ibrahim Suliman
Abstract
Background and aims: Dapagliflozin and empagliflozin are established therapy for chronic heart failure across the ejection-fraction spectrum. Their pivotal trials were powered for a composite of cardiovascular death and worsening heart failure