TL;DR
It is reported that the rs763780 polymorphism may be associated with risk of developing gastric cancer in the population studied, particularly in alcohol drinkers.
It is suggested that SYNE1 rs2295190 may be associated with OSCC progression rather than overall disease susceptibility, particularly in the context of betel quid exposure.
Background/Aim: Colorectal cancer is the second most common cancer in women and the third most common in men. It is the third leading cause of cancer death worldwide. Statistics suggest a worrying increase in the incidence of this cancer in the coming years. Many factors, including family history, age, smoking habits a...
Single nucleotide polymorphisms (SNPs) in the interleukin-17F (IL-17F) gene may modulate inflammatory responses, with distinct effects on inflammation and tumour progression. Helicobacter pylori infection, a Group 1 carcinogen, is strongly associated with gastric cancer (GC) development. This study investigated the inf...
The CYP1A1 rs1048943 polymorphism was not associated with laryngeal cancer susceptibility in this Sudanese cohort, and larger studies are needed to clarify the genetic basis of laryngeal carcinogenesis.
The findings suggest that common IL-4 promoter variants are unlikely to be major genetic determinants of childhood ALL risk, although larger studies in diverse populations are warranted to validate these observations.
Background/Aim: Matrix metalloproteinase-13 (MMP-13) plays an important role in extracellular matrix remodeling and has been implicated in the susceptibility and progression of several malignancies. However, the contribution of MMP-13 genetic polymorphisms to childhood acute lymphoblastic leukemia (ALL) remains unknown...
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