Open access
Skin biopsy in adult-onset Still’s disease: A specific, rapid, and widely available diagnostic test
Derrick H. Y. Chong
Caroline Spaner
Ibrahim Elsharawi
M. Trinder
Haya Al Bitar
M. Goubran
A. Perrotta
Rachael Horner
Dilys Chen
Jennifer Corpuz
Kun Huang
Trudy Taylor
I. M. Lano
Kerri Purdy
J. Dutz
S. Pasternak
R. Crawford
Lu-Ke Y. C. Chen
Medicine
Abstract
AOSD is challenging to diagnose. Chong et al. examine the clinical utility of skin biopsy, an inexpensive and widely available test, in 16 patients with AOSD. They demonstrate that dyskeratotic keratinocytes in the superficial layers are useful for diagnosing AOSD.