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MultiFair: Multimodal Balanced Fairness-Aware Medical Classification with Dual-Level Gradient Modulation

Md Zubair Hao Zheng Grayson W. Armstrong Lucy Q. Shen Gabriela Wilson Yu Tian Xingquan Zhu Min Shi
Oct 2026
Artificial Intelligence Machine Learning Computer Vision

Abstract

Medical decision systems increasingly rely on data from multiple sources to ensure reliable and unbiased diagnosis. However, existing multimodal learning models fail to achieve this goal because they often overlook two critical challenges. First, various data modalities may learn unevenly, thereby converging to a model biased towards certain modalities. Second, the model may emphasize learning on certain demographic groups causing unfair performances. The two aspects can influence each other, as different data modalities may favor respective groups during optimization, leading to both imbalanced and unfair multimodal learning. This paper proposes a novel approach called MultiFair for multimodal medical classification, which addresses these challenges with a dual-level gradient modulation process. MultiFair dynamically modulates training gradients regarding the optimization direction and magnitude at both data modality and group levels. We evaluate MultiFair on three real-world medical classification datasets with diverse demographic attributes,including multiclass classification and missing-modality settings. Experimental results demonstrate its effectiveness.

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