Aug 2026· Microchimica Acta· Vol 193· 0 citations· 41 references
Medicine
TL;DR
A targeted multifunctional nanotherapeutic platform by integrating ferroptosis induction, gene modulation, and chemotherapeutic intervention with highly sensitive and selective miRNA-21 sensing capability is established, laying the groundwork for precision tumor therapy.
In vitro and in vivo experiments demonstrate that the self-reinforcing cycle between autophagy and ferroptosis significantly enhances tumor suppression and suggests that targeting iron-autophagy crosstalk with nanomaterials represents a promising strategy for cancer treatment.
Chen-Shuo Wang, Zhen-Zhen Ma, Meng-Yu Liu et al.· European journal of pharmace...· 0 citations
The DDS provides a promisingly transformable therapeutic platform for drug resistant cancers, and for targeting other and multiple oncogenic miRNA-21 and multiple oncogenic miRNAs.
Qian Guo, Jun-Yang Chen, Yu-Lu Wang et al.· Small· 0 citations
The developed carbon-based nanoplatform showed significant tumor specificity and inhibition, making it a significant approach for a potential multifunctional treatment strategy for cancer.
Z. Sarkar, Varshini Are, Bhavesha Chanchlani et al.· ACS Applied Nano Materials· 0 citations
Cerium molybdate-doped polyaniline nanoparticles are developed to enable a synergistic combination of photothermal therapy (PTT) and CDT, thereby triggering immunogenic cell death (ICD) and enhancing antitumor immunity and presenting a robust nanoplatform integrating chemodynamic and photothermal therapies for potent c...
This work presents a mitochondria-targeted, ROS-activatable supramolecular delivery nanoplatform for self-amplifying redox imbalance and reversing cisplatin resistance for enhanced cisplatin-based cancer therapy.
Ying Liu, Zong-Tao Zhou, Wei Ma et al.· International journal of pha...· 0 citations