In the search for new particles in high-energy physics, it is necessary to first define the signal region (SR) enriched in signal events, and then compare events in this region with the expected background distribution. While most existing search methods rely on prior domain knowledge of either the signal or the background, there has been less effort to relax both assumptions simultaneously, as methods that weaken one assumption typically rely on strong knowledge of the other. We propose Model-Agnostic Search with Smearing and Imperfect Background (MASSIB), a method that addresses this challenge by learning the density ratio of events relative to a misspecified background distribution using modern tools from machine learning, and defining the SR as the region with high density ratio. Recognizing that a naive application of this idea introduces significant bias in background estimation when interpolating from the control region to the SR, MASSIB mitigates this issue by introducing a"smeared"density ratio, which can be learned efficiently through data-level manipulation and used to define an SR that allows for accurate background estimation. By applying it to various types of simulated Large Hadron Collider (LHC) events with realistic background mismodeling, we demonstrate that MASSIB identifies a data-driven SR that achieves high signal concentration consistently across different types of signals while avoiding bias in background estimation. The method does this without making strong assumptions about either the signal or background distribution. We then show that this robustness extends to the validity and strong statistical power of the resulting hypothesis tests for signal detection, demonstrating the potential of this approach for future model-agnostic searches at the LHC.
This paper investigates developing real-world perception for active agents, proposes Gibson Environment for this purpose, and showcases a set of perceptual tasks learned therein.
F. Xia, Amir Zamir, Zhi-Yang He et al.· 2018 IEEE/CVF Conference on...· 1,069 citations· ⚡112
The results indicate that software engineering work practices are chosen opportunistically, adapted and configured to provide value under the constrains imposed by the startup context.
Nicolò Paternoster, Carmine Giardino, M. Unterkalmsteiner et al.· Information and Software Tec...· 394 citations· ⚡54
The possibility of inferring high-dimensional data inference in a model that consists of a prior and an auxiliary differentiable constraint given some additional information is considered, thereby allowing a range of potential applications in adapting models to new domains and tasks.
Alexandros Graikos, Esmeralda S. Whitammer, N. Jojic et al.· Neural Information Processin...· 316 citations· ⚡15
It is proved that any global minimizer of the trajectory balance objective can define a policy that samples exactly from the target distribution, and empirically demonstrate the benefits of the trajectories balance objective for GFlowNet convergence, diversity of generated samples, and robustness to long action sequenc...
Esmeralda S. Whitammer, Moksh Jain, Emmanuel Bengio et al.· Neural Information Processin...· 302 citations· ⚡60
An algorithm is proposed which leverages disentangled semantic factors to generate adversarial perturbation by altering controlled semantic attributes to fool the learner towards various "adversarial" targets.
Haonan Qiu, Chaowei Xiao, Lei Yang et al.· arXiv.org· 208 citations· ⚡17
This work proposes a HALO that directly maximizes the utility of generations instead of maximizing the log-likelihood of preferences, and suggests that the best loss depends on the inductive biases most appropriate for a given setting, an oft-overlooked consideration.
Research Manager Mike Walker reflects on a career spanning hacker culture, cybersecurity, and AI, sharing lessons about trust, teamwork, leadership, and why solving difficult problems requires curiosity, judgment, agility—and an understanding of the rules. The post Learn the rules: The hacker mindset appeared first on Microsoft Research.
Learn how Google Antigravity and our Cheminformatics Skills accelerate drug discovery workflows, search compounds, and propose novel rigidified macrocycles.
MIT News · Artificial Intelligence· news.mit.eduOct 28, 2026
Professor Paris Smaragdis develops computers with superhuman hearing for applications like speech recognition, music understanding, and environmental monitoring.
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