Aug 2026· JAMA Network Open· Vol 9, pp. e2626716· 0 citations· 26 references
Medicine
TL;DR
Findings suggest certain risk factors are shared across populations, representing a critical first step in defining CRC risk profiles to tailor prevention and early detection efforts in the region.
Abstract
Key Points Question Are colorectal cancer (CRC) risk factors identified in high-income populations also associated with CRC risk in adults in Nigeria? Findings In this case-control study of 2063 individuals in Nigeria, including 632 patients with CRC matched with 1431 controls, 5 factors significantly associated with CRC were identified: family history of cancer, adult height, body size or type, processed meat intake, and physical activity. There were no associations with diabetes, smoking, or intakes of red meat, fruit, vegetables, fiber, or alcohol. Meaning These findings suggest certain risk factors are shared across populations, representing a critical first step in defining CRC risk profiles to tailor prevention and early detection efforts in the region.
The evidence that living with overweight or obesity, having a tall body height, or living with diabetes mellitus associates with an increased risk of CRC is strengthened, and education level or physical inactivity were not statistically significant risk factors for CRC.
Emilia Muhonen, K. Seppä, H. Ryynänen et al.· International Journal of Can...· 0 citations
Gender-specific analyses revealed higher tobacco smoking-attributable PAFs in young men and higher obesity-related PAFs in young women, contributing to understanding the distinct etiology of early-onset CRC and highlighting the need for age-specific prevention strategies.
M. S. Seyyedsalehi, P. Boffetta· European Journal of Cancer P...· 0 citations
Evidence from recent studies conducted in Pakistan shows the immediate need for specific public health interventions, better genetic counseling infrastructure, and culturally appropriate mass awareness campaigns to lessen the breast cancer burden at a national level.
Rehana Kouser, Madiha Sadia, S. Abbasi· Journal of Human Centered Te...· 0 citations
Objective: To describe colorectal cancer (CRC) screening status and identify associated factors among adults aged 45-74 years in Can Tho City, Vietnam. Methods: This analytical cross-sectional study included 600 participants from 12 clusters. Frequencies, proportions, and adjusted odds ratios (aORs) were estimated usin...
Phuong Nguyen· International Journal of Hea...· 0 citations
Even light-to-moderate alcohol consumption was associated with increased CRC risk; therefore, strict restriction of alcohol intake may help reduce this risk, particularly among individuals with IFG or diabetes.
Tae-Se Kim, Kyungdo Han, Young Eun Oh et al.· Journal of the National Canc...· 0 citations
Key Points Question Given that cancer incidence is higher among males than among females globally, to what extent do modifiable lifestyle behaviors and health conditions contribute to this disparity by sex across diverse populations? Findings In this multicohort study of 589 766 adults in China and the UK, 11 measured...
