Oct 2026· In Silico Pharmacology· Vol 14· 0 citations· 76 references
Medicine
TL;DR
The proposed MEVC demonstrated favorable predicted immunogenicity, favorable structural characteristics, broad population coverage, and favorable expression characteristics, which support experimental validation and development of a preventive strategy against Hantavirus infection.
Rift Valley fever virus (RVFV) is a major zoonotic pathogen causing significant outbreaks in humans and livestock, with no licensed effective vaccines currently available and reverse vaccinology and immunoinformatics approaches were employed to design three multi-epitope mRNA vaccine candidates against RVFV.
E. K. Oladipo, James Akinwumi Ogunniran, Biobele Winner Sokari et al.· Discover Immunity· 0 citations
Human Adenovirus (ADV), a member of the Adenoviridae family, is Double-Stranded DNA (DSDNA) virus associated with gastroenteritis, conjunctivitis, and severe respiratory infection and illnesses in infants and immunocompromised individuals. Despite its widespread prevalence in food and water sources, no specific and eff...
Arshad Iqbal· Global Journal of Pharmacy &...· 0 citations
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis), remains one of the leading causes of mortality from infectious diseases worldwide, underscoring the urgent need for more effective vaccine strategies. Advances in immunoinformatics have enabled rational, cost-effective vaccine design through sys...
Sema Karabudak, S. Altunok, Emre Can Buluz· Fabad journal of pharmaceuti...· 0 citations
An immunoinformatics-guided reverse vaccinology approach to design novel BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against HMPV identified BAFF- and APRIL-containing multi-epitope constructs with favorable predicted antigenic, physicochemical, structural, and immunological characteristics that warrant...
Reham M. Alahmadi, M. Awadalla, Halah Z. Al-Rawi et al.· Frontiers in Virology· 0 citations
The Oropouche virus (OROV) is an emerging zoonotic orthobunyavirus responsible for recurring outbreaks of febrile illness and neurological disorders in South and Central America. Despite its growing public health issues, no FDA-approved vaccines or antiviral therapies currently exist. To address this gap, a multiepitop...
Jwel Sharma, Ahmad Abdullah Mahdeen· PLoS ONE· 0 citations
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