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Open access Aug 2026

Selenium predominance in heavy metal mixtures is associated with hyperuricemia in Chinese adults: the role of insulin resistance

Insulin resistance might be a crucial mediated pathway between Se and outcomes and three multi-pollutant models revealed positive associations between metal mixtures and SUA as well as HUA, with Se being the primary contributor.

Jing-Fu Lai, Ya-Qin Zhang, Yun-Ting Zhang et al. · 0 citations
Open access Aug 2026

Potential joint association between urinary metal mixtures and adult asthma: A matched case-control study in China.

The findings suggest an association between urinary multi-metal mixtures and adult asthma but do not establish causality and suggest potential nonlinear and pairwise patterns involving multiple metals, particularly U, Ti and vanadium (V), but these findings were exploratory and do not establish synergistic toxicity.

Yu-Jia Qin, Jing-Yi Liang, Qi-Qi Liu et al. · 0 citations
Open access Sep 2026

Associations of Plasma Metal Exposure With the Risk and Severity of Acute Coronary Syndrome: Evidence From Epidemiological and Adverse Outcome Pathway Analyses.

BACKGROUND Evidence links environmental metal exposure to cardiovascular disease, but its association with acute coronary syndrome (ACS) risk and severity remains insufficiently characterized. METHODS This case-control study included 413 newly diagnosed patients with ACS and 413 controls matched 1:1 by sex and age (w...

Ze-Yuan Fu, Zhong-Xian Hua, Zi-Yang Huang et al. · 0 citations

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