Aug 2026· Frontiers in Bioinformatics· Vol 6· 0 citations· 76 references
Medicine
TL;DR
TransCat, a hybrid CNN-Transformer architecture for medical image segmentation, is proposed and an extended deformable attention mechanism with attentive value identification is developed, to control the computational burden caused by the enlarged token set.
Abstract
Medical image segmentation is a fundamental task in computer vision and plays an important role in clinical diagnosis and treatment planning. Existing methods are mainly built on either convolutional neural networks (CNNs) or Transformer-based encoder-decoder architectures. CNNs are effective at capturing local patterns, whereas Transformers are better suited to modeling long-range dependencies. However, current hybrid designs still face three persistent challenges: insufficient exploitation of multi-scale CNN features for global modeling, rapidly increasing attention cost after token expansion, and ineffective fusion between CNN and Transformer representations. To address these issues, we propose TransCat, a hybrid CNN-Transformer architecture for medical image segmentation. First, we introduce Patch Concat, which converts multi-scale CNN features into patch tokens and feeds them jointly into the Transformer, enabling global reasoning across multiple scales. Second, to control the computational burden caused by the enlarged token set, we develop an extended deformable attention mechanism with attentive value identification. Third, we design a Kolmogorov–Arnold Network (KAN) attention module for adaptive cross-branch fusion. The module projects high-level CNN and Transformer features into a shared space and uses a KAN layer to estimate data-dependent pixel-wise weights. These weights selectively modulate the globally modeled Transformer features, allowing complementary local structural evidence from the CNN branch to be incorporated according to the image content rather than through fixed addition or concatenation. Experiments on multiple medical image segmentation benchmarks show that TransCat is competitive under the reported protocols, with its clearest advantage observed on unseen polyp test data.
The proposed framework is intended to support clinical image assessment and prioritization rather than replace expert diagnosis, and demonstrates the potential of hybrid CNN-Transformer architectures for robust and scalable computer-assisted multi-disease screening from medical imaging data.
M. Balakrishnan, K. Ananthi, S. R. et al.· International journal of com...· 0 citations
A hybrid CNN-Transformer architecture guided by channel attention, referred to as CACFormer, for 3D medical image segmentation, and a novel linear Transformer variant that integrates a linear attention mechanism with tanh activation are introduced.
Hongzhong Tang, Xiaopei Zhang, Yabo Li et al.· IEEE Transactions on Medical...· 0 citations
GTUNet is proposed, a novel hybrid framework that synergistically integrates Graph Attention Networks, Transformers, and UNet for robust 3D medical image segmentation and significantly outperforms existing methods in ASSD, highlighting its precision in delineating vascular boundaries.
Mengjun Sheng, Shan-Shan He, Zhiyu Shi· Signal, Image and Video Proc...· 0 citations
GLNet adopts a dual-branch encoder that combines a CNN-based Local Detail Perception Branch with a Mamba-based Global Context Modeling Branch, enabling the joint extraction of fine-grained local features and long-range semantic representations.
Multi-Scale CNN Token Transformer (MSCT-Trans), a lightweight and interpretable hybrid architecture for general-purpose ultrasound image classification, is proposed, which consistently outperformed CNN and Transformer baselines across accuracy, macro-F1 and area under the receiver operating characteristic curve, partic...
Mohsin Furkh Dar, Sayima Mukhtar· Ultrasound in Medicine and B...· 0 citations
The results show that larger models and larger pretraining datasets do not automatically lead to better downstream performance, and transfer effectiveness in medical imaging is driven primarily by architectural inductive biases, pretraining strategy, and domain relevance.
Dina A. Elkholy, Mohamed S. Shehata, John W. Braun· Journal of imaging informati...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.