Skip to content
Review Open access

Effects of saffron and crocin on glycemic control: an exploratory systematic review and meta-analysis of randomized trials

Nov 2026 · medRxiv · 0 citations
Medicine

TL;DR

Saffron and crocin were associated with lower fasting glucose and HOMA-IR, whereas the HbA1c estimate remained compatible with both a reduction and little difference, although variation in populations, preparations, and trial sizes limits interpretation of the average effects.

Read PDF

Similar papers

Review Open access Oct 2026

Comparative effectiveness of turmeric and curcumin formulations on glycemic, lipid, and inflammatory markers in people with prediabetes: A systematic review and network meta-analysis.

Overall certainty of evidence was low due to heterogeneity and short trial durations, and variability among combination formulations, in prediabetes, but formulation-specific metabolic effects were observed.

Phatcharaporn Khongphakdee, Jaruwan Jumnianpol, Panupong Puttarak et al. · 0 citations
Review Open access Oct 2026

The effect of dietary nitrite/nitrate on glycaemic control: a systematic review of randomized controlled trials using beetroot-derived preparations

No consistent or significant improvements in glycaemic indices were observed, suggesting that dietary nitrate/nitrite, particularly from beetroot, is not effective for glycaemic control.

Ali Jamshidi, Hadith Tangestani, Z. Yari et al. · 0 citations
Review Oct 2026

Effects of Walnut Consumption on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Dose-Response Meta-Analysis.

BACKGROUND Inflammation and dysregulation of adipokines play key roles in the development of metabolic and cardiovascular disorders. Walnuts (Juglans regia L.), rich in polyunsaturated fatty acids, fiber, and antioxidants, may modulate inflammatory and metabolic pathways; however, evidence from interventional studies r...

G. Mashayekhi, D. Ashtary-larky, Mehdi Karimi et al. · 0 citations
Review Open access Sep 2026

Effects of Curcumin Supplementation on Inflammatory Biomarkers in Adults with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Curcumin or curcuminoid supplementation may reduce hs-CRP and TNF-α in adults with T2DM; however, the strength of inference is limited by the small evidence base, heterogeneity, and inconsistencies in outcome reporting.

Claudio Ignacio Pérez, J. González-Casanova, D. Rojas-Gómez · 1 citation
Open access Sep 2026

A meta-analysis of the effects of Zingiber officinale on metabolic indices among patients with type 2 diabetes

Abstract The metabolic effects of ginger (Zingiber officinale) on type 2 diabetes have been increasingly assessed in clinical trials, but the results remain inconsistent. In this updated meta-analysis, the Cochrane Library, Scopus, PubMed, Web of Science, and Google Scholar were searched from the inception to November...

Qian-Jun Li, Min Li, Misbah Ullah Khan et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.