TL;DR
A systematic analysis provides evidence supporting a potential causal relationship between four gut microbiota taxa including class.
Negativibacillus massiliensis is likely associated with an increased risk of AD, and v-VLDL FC/TL may partially mediate this association, suggesting their potential as targets for AD prevention and treatment.
Genetic evidence is provided that gut microbiota influence CKD risk partially through circulating metabolites, highlighting the gut microbiota–metabolite–CKD axis as a potential therapeutic target.
The results indicate that the gut microbiota has causal effects on DKD and that immune cell traits exert a mediation effect to some extent.
Previous studies have investigated the relationship between gut microbiota (GM) and oral lesions, but the reported associations across microbial taxa and oral conditions have been inconsistent. This 2-sample Mendelian randomization study using summary-level GWAS data aimed to clarify the causal links between GM and 5 o...
This study provides genetic evidence supporting a bidirectional causal relationship between specific saliva and gut microbiota and bone neoplasm-related phenotypes and identifies several microbial taxa as potential candidates for future biomarker development and therapeutic investigation in bone neoplasm-related phenot...
Genetically predicted IBS risk was associated with lower abundances of Turicibacter and Slackia, whereas no robust reverse associations were observed for FD, and several microbial taxa are identified as candidates for further mechanistic and clinical validation rather than established risk factors or therapeutic target...
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