Jul 2026· European Review of Aging and Physical Activity· 0 citations
Medicine
TL;DR
LLMs, particularly Claude, ChatGPT-4 and Deepseek demonstrate strong potential for generating accurate, safe, and hallucination-free exercise awareness messages for older adults, however, readability remains above recommended levels, requiring optimization.
Abstract
Background
Large Language Models (LLMs) are emerging as potential tools for health communication and patient education. However, their ability to translate complex medical guidelines into accessible, safe, and accurate messages for older adults remains insufficiently evaluated. To assess the capacity of ChatGPT-4, Claude AI, and Deepseek to generate exercise awareness messages for older adults, aligned with international expert consensus.
Materials And Methods
This was a cross-sectional observational study conducted between April and August 2025. Using the ICFSR 2021 Global Consensus on optimal exercise recommendations as the gold standard, we evaluated messages generated by three LLMs for 13 common chronic conditions in older adults. A standardized prompt was used to generate messages addressing exercise prescription considerations, disease progression, and recommended modalities. Two independent expert evaluators; a geriatrician and a sports medicine physician assessed five dimensions using a 5-point Likert scale; accuracy, clarity, safety, behavioral relevance, and absence of fabrication. Readability was measured using Flesch-Kincaid Grade Level (FKGL), Gunning Fog Index (GFI), and Simple Measure of Gobbledygook (SMOG). Inter-rater agreement was assessed using intraclass correlation coefficient (ICC).
Results
Claude achieved the overall scores from both evaluators at 4.63 ± 0.55 and 4.60 ± 0.55, followed by ChatGPT-4 at 4.55 ± 0.50 and 4.48 ± 0.53 and Deepseek at 4.15 ± 0.87 and 4.17 ± 0.86. Inter-rater agreement was moderate was 0.668. Claude demonstrated accuracy scores at 4.58 ± 0.64, while ChatGPT-4 excelled in clarity with 5 ± 0. All models achieved perfect scores for absence of fabrication (5 ± 0). Readability indices revealed high complexity across all LLMs, with median FKGL values ranging from 10.84 to 10.93, corresponding to 10th-11th grade reading level, exceeding recommended levels for older populations. A significant correlation was found between Claude's accuracy scores and FKGL (r = 0.599, p = 0.030).
Conclusion
LLMs, particularly Claude, ChatGPT-4 and Deepseek demonstrate strong potential for generating accurate, safe, and hallucination-free exercise awareness messages for older adults. However, readability remains above recommended levels, requiring optimization.
This mixed-methods evaluation suggests that a deliberately constrained, language-focused AI system can improve the accessibility of medical notes while preserving clinical accuracy and safety while extending into clinical interpretation.
Nicholas Lamb· Frontiers in Digital Health· 0 citations
Abstract Background Large language models (LLMs) are increasingly used to generate health education materials, yet questions remain about whether LLM-generated content can balance professional accuracy with public accessibility and what ethical challenges may arise during deployment. Objective This study aimed to evalu...
Tian-Yi Xu, Yong Yin, Xi Zhang et al.· Journal of Medical Internet...· 0 citations
While ChatGPT provided generally acceptable clinical information, variability in readability and expert ratings raises patient safety concerns and AI-generated health content should be reviewed and tailored to older adults' health literacy needs before clinical use.
Merve Arı, N. Ilçin, Hatice Yağcıoğlu et al.· Revista da Associação Médica...· 0 citations
OBJECTIVES
In older adults with multimorbidity, clarifying the treatment goals is essential. The Outcome Prioritization Tool (OPT) is an internationally used four-item questionnaire (Independence, Staying alive, Pain relief, and Symptom relief). This study aimed to create a linguistically valid Japanese version of the...
Takuma Kimura, Saki Munakata, Hiroshi Nin et al.· Nihon Ronen Igakkai zasshi....· 0 citations
Large language models (LLMs) are increasingly used in primary care for documentation, patient communication, and clinical decision support. However, many clinicians are adopting these tools for patient care without structured training or a clear understanding of their limitations. LLM output may appear authoritative bu...
Christopher R. Stephenson, Christopher A. Aakre, I. Croghan et al.· Journal of Primary Care & Co...· 0 citations
These findings support supervised use of large language models and evaluation approaches that assess reasoning and prioritisation as well as target detection and should not be interpreted as evidence that one model is clinically superior in real-world practice.
Kubra Cingar Alpay, D. Ozata, T. Gedik et al.· BMC Geriatrics· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.