Skip to content
Open access

Effect of Propofol versus Sevoflurane on Postoperative Shivering during Maintenance of General

Jul 2026 · International Journal of Pharmaceutical Quality Assurance · 0 citations · 19 references

Abstract

Background: The choice of anesthetic agent for maintenance of general anesthesia significantly influences intraoperative stability, ‘ recovery profile, and postoperative outcomes. Propofol and sevoflurane are commonly used agents, yet their comparative performance remains clinically relevant. Aim: To compare propofol and sevoflurane for maintenance of anesthesia with respect to hemodynamic stability, recovery characteristics, and adverse events. Methodology: This prospective, randomized comparative study included 80 ASA I–II patients undergoing elective surgeries. Patients were allocated into two groups: Group P (propofol infusion) and Group S (sevoflurane inhalation). Hemodynamic parameters, recovery times, Modified Aldrete Score, and perioperative adverse events were assessed and analyzed statistically. Results: Demographic variables were comparable between groups. Group P demonstrated significantly better intraoperative hemodynamic stability with lower heart rate and blood pressure values (p < 0.05). Recovery was faster in Group P, with shorter times to eye opening, verbal response, and extubation (p < 0.001). Postoperative nausea, vomiting, and emergence agitation were significantly lower with propofol. Conclusion: Propofol provided superior hemodynamic control, faster recovery, and fewer postoperative adverse effects compared to sevoflurane, making it a preferable agent for maintenance of anesthesia in short elective surgeries.

Read PDF