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VEZF1 facilitates pluripotency exit by regulating developmental transcriptional programs and CTCF occupancy

Isaiah K. Mensah Minghao He Mudasir Zahoor S. U. Khan Martin L. Emerson Hern J. Tan Geordan D. Bolden S. Utturkar H. Gowher
Aug 2026 · bioRxiv · 0 citations · 53 references
Biology

TL;DR

A novel function for VEZF1 is identified in coordinating pluripotency exit with expression of pro- differentiation signaling genes and a functional interplay between VEZF1 and CTCF during cell state transitions is revealed.

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