Causal effect of household income on Alzheimer's disease risk and mediation by cognitive performance: a bidirectional, two‑sample, two‑stage mendelian randomization study

Combined Effects of Social Determinants of Health on Alzheimer's Disease: Insights from Bibliometric and NHANES Analyses.

Investigating the Causal Relationship between Neuroticism and Alzheimer's Disease Using Mendelian Randomization and the Mediating Role of Modifiable Risk Factors

Depression, hypertension, hypertension, and alcohol consumption were identified as significant mediators of the relationship between higher neuroticism and increased AD risk, suggesting that the neuroticism-AD relationship is unlikely to be causal.

The Joint Effects of Life's Essential 8 and Genetics on Mild Cognitive Impairment and Dementia Risk in People With Diabetes: Findings From the UK Biobank and All of Us.

The association between CVH and MCI and dementia was stronger among individuals with low or moderate genetic risk and appeared attenuated among those with high genetic risk.

Genetic evidence for a causal role of depression in late-onset Alzheimer disease: A Mendelian randomization study

Genetic evidence supporting a causal role for depression in the etiology of late-onset AD is provided, a link not observed for other major psychiatric disorders tested and highlighted the specific importance of managing depression as a potential strategy for mitigating AD risk.

Evidence from European ancestry genome-wide association studies and a case-control study suggests several selenoproteins are linked to a decreased risk of Alzheimer's disease

Genetic and clinical evidence is provided that specific selenoproteins are associated with a decreased risk of AD and highlight the potential role of these proteins in AD pathophysiology and suggest their promise as biomarkers or therapeutic targets, warranting further investigation.

Inflammatory dietary patterns and mental health traits in middle/old-aged adults: A bi-directional Mendelian Randomization study