Aug 2026· Analytical and Bioanalytical Chemistry· 0 citations· 30 references
Medicine
TL;DR
A dual electrochemical immunosensing platform based on graphdiyne oxide (GDYO) for simultaneously determining the neutrophil activation biomarkers CD63 and CD66b is developed and practical applicability was demonstrated by analyzing serum samples from healthy individuals and patients diagnosed with chronic obstructive pulmonary disease.
The novel electrochemical immunosensor based on a four-armed star poly(glycidyl methacrylate) polymer containing epoxy side groups (FASPGMA)-coated commercial graphene-paper electrode demonstrated remarkable sensitivity and great anti-interference characteristics when it was applied to the analysis of different biomark...
E. Aydın, Muhammet Aydın, M. Sezgintürk· Microchimica Acta· 0 citations
Citrullinated histone H3 (CitH3) is an emerging biomarker for early sepsis diagnosis. However, its detection based on standard enzyme-linked immunosorbent assay (ELISA) suffers from long analysis time (4–5 h), expensive instruments, and the need for skilled operators, necessitating the development of alternative detect...
V. Primpray, W. Kamsong, A. Sappat et al.· ACS Omega· 0 citations
Multiplexed immunoassays frequently face challenges associated with signal cross-reactivity, matrix effects, and the integration of analytes with disparate concentration ranges and transduction efficiencies. Here, we report an electrochemical multiplexed immunoassay implemented on a four-working-electrode screen-prin...
Direct electrochemical detection of low-abundance biomarkers in serum necessitates the combination of sensitivity, anti-fouling capability, and biocompatibility. In this study, a hierarchically structured biosensing interface of AuNRs@PEG@PEDOT:Hep is constructed that incorporates vertically aligned gold nanorod arrays...
Dong-Liang Chen, Mengpeng Li, Xiang-Ya Wang et al.· Journal of Colloid and Inter...· 0 citations
A label-free, stable, and highly specific electrochemical immunosensor for sensitive detection of OPN, which showed potential for early osteosarcoma diagnosis and ultimately, point-of-care (POC) analysis.
R. P. Swain, Riddhi Dubey, Ankur Singh et al.· ACS Applied Electronic Mater...· 0 citations
C-reactive protein (CRP), a key inflammatory biomarker, plays a critical role in clinical diagnostics; however, its reliable quantification demands analytical methods that surpass the limitations of conventional single-mode detection by integrating high sensitivity with built-in signal fidelity. Herein, we report a dua...
Lin-Ying Cheng, Yu-Feng Zhong, Man-Qi Li et al.· ACS Sensors· 0 citations
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