The therapeutic relevance of N. jatamansi-derived compounds through in-silico evaluation as antiviral agents targeting HIV-1 reverse transcriptase is supported and warrant further in-vitro and in-vivo studies to explore their role as novel antiretroviral agents.
Findings suggest that bioactive compounds from E. officinalis may serve as promising candidates for the development of anti-CHIKV therapeutics, however, further experimental validation is required to confirm their efficacy and safety.
R. Daman, M. Miglani· Genetics and Molecular Resea...· 0 citations
Findings suggest P. macrocarpa phytochemicals may serve as natural alternatives to existing antiviral treatments, warranting further experimental validation.
Fatin Hannani Mohd Shaharizal, N. Alias, Sin-Ang Lee et al.· Malaysian Journal of Science...· 0 citations
It is highlighted that phytocompounds from Hydrocotyle javanica exhibit significant binding affinity toward key enterobacterial targets, along with favorable ADME and toxicity profiles, which suggest their potential as promising lead molecules for anti-enterobacterial drug development, warranting further experimental v...
Debasmita Paul, M. Ghosh, Manab Mandal· Bioresources and Bioprocessi...· 0 citations
Overall, compound 2 exhibited the stronger experimentally measured yeast α-glucosidase inhibition, whereas the computational findings provide target-specific hypotheses rather than confirming multitarget antidiabetic activity.
M. C. Nguyen, Minh-Tri Le, Huynh Nguyen Khanh Tran· RSC Advances· 0 citations
Findings indicate that the tested compounds possess potential as antibacterial and quorum sensing inhibitory agents by targeting LuxR, however, further in vitro and in vivostudies are required to validate their biological activity and therapeutic potential.
Ziyan Iswahyudi, M. Fadjar, Y. Maimunah et al.· Journal of aquaculture and f...· 0 citations
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