Aug 2026· Endocrine· Vol 91· 0 citations· 40 references
Medicine
TL;DR
APOC1 rs4420638 and CXCL8 rs4073 seem to be associated with DN risk in Tunisian T2DM patients both individually and within multilocus genetic profiles.
A strong association of three ADIPOQ variants with DR in the North West Indian population is demonstrated and these variants may contribute to genetic susceptibility and could serve as potential biomarkers for early identification of highrisk individuals.
R. Sikka, K. Matharoo, A. Bhanwer· Research journal of biotechn...· 0 citations
Combined analysis using a genetic risk score suggested that cumulative genetic burden involving PCSK9 and CCL22 variants was associated with an increased risk of MI.
P. K. Chandra Sekar, Ashok Govindaraj, R. Veerabathiran· Functional & Integrative Gen...· 1 citation
The findings suggest that increased insulin resistance and impaired cellular uptake occurred alongside significantly higher C-peptide levels in individuals with the CT/TT polymorphic variants of transcription factor 7-like 2 (TCF7L2) rs1790314.
Idoko Roseline, B. Holy, Onwuli Donatus et al.· Asian Journal of Medicine an...· 0 citations
Predictive evidence was provided suggesting that rs7903146 may have tissue-specific regulatory relevance and may be indirectly linked to metabolic and WNT/β-catenin signaling pathways, and the proposed regulatory mechanisms require experimental validation.
Ahmed M. Ahmed, Hakeemah H Al-Nakhle, Amjad M. Yousuf et al.· Diagnostics· 0 citations
Objective: This study aims to evaluate the association of the insulin receptor substrate 1 (IRS1) rs2943640 single nucleotide polymorphism (SNP) with the effectiveness of glibenclamide therapy in Iraqi diabetic patients treated with glibenclamide.
Methods: This cross-sectional study was conducted in Karbala City, locat...
Mohammed Mahmood Abedalhussein, Mohammed Ibrahim Rasool, Suzanne Jubair Abbas· International Journal of App...· 0 citations
Coronary artery disease (CAD) is a complex disorder influenced by endothelial dysfunction, vascular inflammation, and thrombosis. This study evaluated selected genetic variants in endothelin signaling (EDN1, PHACTR1), nitric oxide metabolism (NOS3), and fibrinolysis (SERPINE1/PAI-1) in relation to CAD susceptibility, m...
A. Ozuynuk-Ertugrul, Berkay Ekici, Ajar Koçak et al.· Clinica chimica acta; intern...· 0 citations
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