Review

Perfusion imaging-guided risk stratification and endovascular decision-making in low-NIHSS large-vessel occlusion stroke: a systematic review and exploratory meta-analysis

Chang-Ya Liu Tao Hu Xin-xin Wu Wen-Chao Chu Xue-Bin Hu

Aug 2026 · Journal of Neurology · Vol 273 · 0 citations · 38 references

Medicine

TL;DR

A systematic review and exploratory meta-analysis of studies evaluating perfusion or hemodynamic imaging in adults with low-NIHSS LVO stroke found large Tmax-defined hypoperfusion volumes, larger perfusion lesion volumes, and impaired hemodynamic reserve were associated with early neurological deterioration or poor functional outcome.

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