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The Type VI secretion effector TpeX expands the pore-forming virulence arsenal of Pseudomonas aeruginosa

Chantal Soscia Sébastien Reig D. Lefebvre Maximilien Rouzaud L. Schmitt B. Ize G. Brasseur S. Bleves
Aug 2026 · bioRxiv · 0 citations · 81 references
Biology

TL;DR

TpeX is identified as a bactericidal, colicin-like pore-forming T6SS effector whose membrane activity is controlled by a cognate immunity protein, thereby expanding the repertoire of membrane-targeting weapons used by P. aeruginosa in interbacterial competition.

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