Aug 2026· Influenza and Other Respiratory Viruses· Vol 20· 0 citations· 12 references
Medicine
TL;DR
A retrospective analysis to detect EV‐D68 in archived samples collected from hospitalized children with SARI in Zambia from 2018 to 2020 identified eight positive samples in 2020, and genetic sequence analysis showed that all sequences belonged to subclade A2.
Abstract
Enterovirus D68 (EV‐D68) is a cause of severe acute respiratory infections (SARI) and is associated with acute flaccid paralysis. However, data on EV‐D68 in Africa, where SARI remains a leading cause of morbidity and mortality among children, remain limited. We conducted a retrospective analysis to detect EV‐D68 in archived samples collected from hospitalized children with SARI in Zambia from 2018 to 2020. We identified eight positive samples in 2020, and genetic sequence analysis showed that all sequences belonged to subclade A2. Continuous monitoring is crucial to enhance understanding of the epidemiology and molecular characteristics of EV‐D68 in Africa.
Enterovirus D68 (EV-D68) primarily causes respiratory illness in children but is also associated with serious neurological outcomes. Although EV-D68 circulation has historically demonstrated a biennial pattern, with peaks during summer and fall, infections can occur year-round, with unpredictable outbreaks. Notab...
Haya Hayek, J. Amarin, Olla Hamdan et al.· Journal of the Pediatric Inf...· 0 citations
Children with EV-D68 respiratory disease commonly presented with severe asthma-like respiratory disease, even in those without atopy, and children quickly improved over short hospitalizations when managed with bronchodilators, steroids, and respiratory support.
Hai Nguyen-Tran, Molly Butler, Dennis Simmons et al.· The Pediatric Infectious Dis...· 0 citations
It is revealed EV-D68 circulated endemically in this pediatric population, establishing a high population immune baseline (>90.0%) with distinct age-dependent patterns and providing key reference data for ongoing serosurveillance, outbreak risk assessment, and the evaluation of future vaccines or immunoprophylactic str...
Li-Ting Wang, Qi-Guo Zhu, Yi Lu et al.· Viruses· 0 citations
This review systematically examines EV infections from multiple perspectives, including epidemiology, virology, viral entry mechanisms, virus‐host interactions, clinical diagnosis and management, prevention and control measures, with the aim of providing insights and references for research on EV pathogenesis, precisio...
Xiang-Peng Chen, Ling-Yun Guo, X. Lei et al.· Pediatric Investigation· 0 citations
NoV infection prevalence rose continuously in Ezhou during the 2.5-year study period, with seasonal peaks in winter and spring, with seasonal peaks in winter and spring.
Dan Luo, Siyue Tang, Yingru Liu et al.· Frontiers in Physiology· 0 citations
Current evidence on the epidemiology, clinical presentation, diagnostic challenges, and prevention of selected arboviral infections in children within the European context are summarized, highlighting persistent gaps in pediatric-specific data and implications for preparedness and public health.
G. Sturniolo, Silvia Garattini, Denis Doni et al.· Viruses· 0 citations
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