TL;DR
The anatomical connections of the NAc with the underexplored brainstem and cerebellar connections are investigated, demonstrating overlapping connections in both species, particularly with the raphe, parabrachial, ventral tegmental area and pontis oralis.
The organizing principle of input and projection of medium spiny neurons across NAc in adult male mice at single-cell resolution was examined, revealing topographic distribution principles of these neurons and their terminals in the substantia innominata (SI) subdivision.
The basal forebrain septum separates the lateral ventricles and comprises the septum pellucidum and septum verum, the latter containing the septal nuclei. These nuclei are involved in cognitive, emotional, and autonomic function and are implicated in psychiatric and neurological disorders, including Alzheimer’s disease...
This work uses cell type-specific retrograde anatomy and ex vivo slice physiology and optogenetics to characterize the properties of synapses onto CINs in the NAc core of mice of either sex, and establishes how these inputs and receptors evoke action potentials and influence spontaneous firing.
This review aims to provide a summary of both the cortico-cerebellar as well as of the cerebello-cortical routes that are used in their interaction, focusing on connections that are involved in motor control.
Evidence is provided that pharmacological and pathological loss of responsiveness involve distinct neurotransmitter system contributions across individual basal ganglia nuclei, offering a novel framework for targeted therapeutic interventions in patients with disorders of consciousness.
Investigations have begun exploringTranscranial direct current stimulation of the cerebellum (ctDCS) as a viable intervention for patients with neurological conditions because of its good safety profile and the ability of ctDCS to modify behavior.
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