This study investigates the extent to which Retrieval-Augmented Generation and Named Entity Recognition improve the quality, factual consistency, and readability of automatically generated lay summaries compared with standard LLM-based generation.
Abstract
Radiology reports are written primarily for clinicians, and their specialized terminology often makes them difficult for patients to interpret. As a result, many patients turn to publicly available Large Language Models (LLMs) to help explain their reports, despite well-documented risks of factual inaccuracies and hallucinations. Automated lay-summary generation has emerged as a promising alternative, yet the effectiveness of retrieval-enhanced and clinically informed approaches for radiology-specific communication remains underexplored. This study investigates the extent to which Retrieval-Augmented Generation (RAG) and Named Entity Recognition (NER) improve the quality, factual consistency, and readability of automatically generated lay summaries compared with standard LLM-based generation. We develop a framework combining NER-based extraction of clinically relevant findings with a RAG mechanism for contextual grounding, evaluated across few-shot and fine-tuned variants of two models (Qwen, BioBART). Results show that NER consistently improves readability and overall quality, while RAG alone offers no benefit and can introduce hallucinations from irrelevant retrieved terms. Combining RAG with NER degrades performance in few-shot settings but improves readability when fine-tuned. Fine-tuned BioBART with NER achieves the best overall performance, highlighting entity-aware extraction as the primary driver of improved patient-friendly summaries.
Radiology reports are often filled with medical jargon that limits patient understanding. Lay summaries can improve understanding but are time-consuming for healthcare providers to create. The objective of this study is to explore the use of tailored prompts for five Large Language Models (LLMs) in generating lay summa...
Nanziba Tasneem, C. B. van der Pol, A. Zahoor et al.· PLOS Digital Health· 0 citations
DPO-Clin is proposed, a novel post-training framework that focuses preference optimization on clinical findings and cross-modal alignment and achieves superior performance over existing DPO-based MRG methods, exhibiting robust generalizability across distinct baseline architectures and diverse medical imaging modalitie...
Qiang Hu, Yuxuan Luo, Yingjie Guo et al.· 0 citations
A rubric for grading AI-generated patient-friendly report quality across core attributes and determining whether such reports are safe for patient distribution may provide a standardized safeguard before release of AI-generated patient-friendly reports.
Bonnie A. Armstrong, Arogya Koirala, Hye Sun Na et al.· AJR. American journal of roe...· 0 citations
Large language models (LLMs) are increasingly proposed for clinical summarization, yet evaluations relying on textual similarity overlook clinically consequential failure modes such as fabrication, omission, contradiction, and negation inversion. We treat medical summarization as controlled clinical compression, operat...
Luis Vera, Olga Craveiro, Ricardo Malheiro et al.· Machine Learning and Knowled...· 0 citations
Digitization of medical records stands out among the most critical obstacles in contemporary medicine due to the unstructured nature of most of the collected clinical data. The traditional approach to text mining and optical character recognition (OCR) proves inefficient when processing the complex seman tics of textua...
Akash Deepak, Varad Bhutada, Rupam Agrawal et al.· International Conference on...· 0 citations
MERGE-Med is a hybrid multi-expert architecture that consists of a mixture-of-experts (MoE) layer with three domain-specialized LLaMA-3 8B models for diagnostic reasoning, treatment protocol generation, and patient-friendly communication and a contrastive fine-tuning framework validated by an ensembled DeBERTa-v3-large...
D. S. Tejaswi, P. R. Reddy, K. Shailaja et al.· Conference Proceedings in Sc...· 0 citations
Related blog posts
Microsoft Research Blog· microsoft.comOct 22, 2026
Flint-interactive gives AI agents a language for creating interactive visualizations. Click a chart, filter data, highlight related content, and explore beyond the view the author originally chose. The post Flint-interactive: A language for creating interactive data visualizations appeared first on Microsoft Research.
A new computational approach reveals how cells communicate to assemble into tissues. This could accelerate stem cell engineering, improve disease models, and inform therapies.
Microsoft Research Blog· microsoft.comOct 15, 2026
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.