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Dosimetric and spatial impact of high-resolution SPACE MRI on target delineation for glomus tumor radiosurgery: a retrospective cohort study

Jul 2026 · Journal of Neuro-Oncology · Vol 179 · 0 citations · 35 references
Medicine
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Residual intrafraction motion produced directionally asymmetric coverage loss, with the largest effect on the boosted GTV, and motion-inclusive dose reconstruction enabled derivation of practical asymmetric margins that improved robustness while identifying the tradeoff between target coverage and delivery efficiency.

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Dosimetric Impact of Deformable Image Registration versus Simple Summation in Multi-Fraction HDR Brachytherapy for Cervical Cancer under Standard Protocol

DIR-based dose accumulation resulted in significantly lower HR-CTV dose estimates compared with SS, while dose differences for the bladder and rectum remained minimal, and future research should correlate DIR-based dosimetry with clinical outcomes to support anatomically adaptive brachytherapy.

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Early target volume dynamics during MR-guided radiotherapy for glioblastoma: first results from the prospective MARGA-I trial.

BACKGROUND Serial MRI during radiotherapy may enable early response assessment and guide adaptive treatment strategies; however, data on intratreatment volumetric changes remain limited. We herein report results of the MARGA-I-study, investigating target volume changes during MR-linac-based radio-(chemo-)therapy. MAT...

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Forward-Planned Multisegmented Technique in Resource-Limited Settings: A Feasible Dosimetric Upgrade for 3D-CRT in Locally Advanced Nasopharyngeal Carcinoma

In resource-limited settings, intensity-modulated radiotherapy (IMRT) is often unavailable, forcing reliance on three-dimensional conformal radiotherapy (3D-CRT) for advanced nasopharyngeal carcinoma (NPC). This limits curative potential due to challenges in sparing organs-at-risk (OARs) while covering complex target v...

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Clinical impact of setup shift application on image registration for hypofractionated prostate cancer treatment

Daily CBCT image-guided couch corrections maintain dosimetric accuracy during hypofractionated prostate radiotherapy and support safe implementation of tight PTV margins in resource-constrained public-sector healthcare settings.

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