Sustainable UHPLC-MS/MS assay for ultra-sensitive simultaneous quantification of amoxicillin and flucloxacillin with application to a bioequivalence study.

A sensitive and high-throughput LC-MS/MS method for the determination of ibuprofen: Application to a gender-comparative pharmacokinetic study

A sensitive and reliable ultra-high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of ibuprofen in plasma to investigate the pharmacokinetics of ibuprofen after oral administration of ibuprofen sustained-release capsules.

SIL-IS LC-MS/MS method for rapid quantification of phloroglucinol in human plasma: development, validation and application to a pharmacokinetic study.

A sensitive, rapid, and robust liquid chromatography-tandem mass spectrometry method incorporating a stable isotope-labeled internal standard incorporating phloroglucinol-13C6 was developed and validated and successfully applied to a pharmacokinetic and bioequivalence study of phloroglucinol orally disintegrating table...

A validated bioanalytical LC-MS/MS method for the simultaneous determination of molnupiravir, N-hydroxycytidine, and baricitinib in human plasma.

A sensitive and validated liquid chromatography-tandem mass spectrometry method was developed for the simultaneous quantification of the anti-COVID-19 agents molnupiravir, its active metabolite N-hydroxycytidine (NHC), and baricitinib in human plasma, and met the acceptance criteria.

BIOANALYTICAL LC-MS METHOD FOR DETECTION AND QUANTIFICATION OF NIFURTIMOX IN HUMAN PLASMA

Objective: Nifurtimox is a type of nitrofuran derivative employed for treating sleeping sickness as well as Chagas disease. The aim is to develop and validate a precise and specific liquid chromatography mass spectrometric technique for the estimation of Nifurtimox in human plasma.Material and Method: Chromatographic s...

An Lc-Ms/Ms Method Development and Validation for the Quantification of Lurbinectedin in Biological Matrices; Application to Kinetic Study in Rabbits

The findings regarding accuracy, specificity, sensitivity, matrix effect, recovery and stability findings of Lurbinectedin in plasma samples for the established method highlight its significance in bioequivalence and pharmacokinetic studies.

Rapid and validated LC-APCI-MS/MS method for determination of N-nitroso vonoprazan in pharmaceutical products.