TL;DR
In conclusion, QQ enzymes represent a promising and sustainable approach to controls bacterial pathogenicity and biofilm-associated infections.
This comprehensive analysis underscores QS interference as a versatile and sustainable strategy, while charting a course for its evolution from a laboratory phenomenon to a practical solution.
The potential of mushrooms as a source of novel QSIs is discussed, as reflected in their diverse bioactive compounds, multidirectional mechanisms of action, species-specific activity, and synergistic interaction with conventional antibiotics.
Pseudomonas aeruginosa employs quorum sensing (QS) to coordinate biofilm formation and virulence factor expression, positioning QS as a promising target for anti-infective interventions. This study evaluated the antibiofilm and antivirulence efficacy of 2-methoxy-1,4-naphthoquinone (MNQ), a natural naphthoquinone, agai...
The increasing prevalence of multidrug-resistant (MDR) Pseudomonas aeruginosa has reduced the effectiveness of conventional antibiotics and necessitated the development of alternative therapeutic approaches. Quorum sensing (QS), a bacterial cell-to-cell communication system that regulates virulence factor productio...
Quorum sensing (QS) is a key component of microbial communication, which controls collective behaviours in response to cellular density. Microbial organisms are mainly able to coordinate a number of physiological functions, including sporulation, motility, biofilm formation, pathogenicity, antibiotic resistance, and th...
It is suggested that integrating QSIs into clinical practice could completely alter the management of bacterial infections and reduce the growing problem of AMR.
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