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Integrative multi-omics analysis of DNA methylome and transcriptome in a tyrosine kinase inhibitor LPM4870108-induced rat model of obesity

Jul 2026 · International Journal of Obesity · Vol 50, pp. 2034 - 2044 · 0 citations · 60 references
Medicine

TL;DR

Findings indicate that LPM4870108-stimulated hyperphagia and weight gain were associated with DNA hypomethylation and concomitant upregulation of the AVP gene.

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