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Artificial intelligence model: optimizing cancer risk level predictions using machine learning and deep learning approaches

Aug 2026 · bioRxiv · 0 citations · 60 references
Biology

TL;DR

The RF model’s ability to effectively estimate cancer risk levels among individuals, allowing for earlier discovery and more effective medical care is demonstrated, resulting in reliable generalization and accuracy estimates.

Abstract

This study emphasizes the potential of computational techniques in cancer risk assessment, highlighting opportunities for specific and data-driven healthcare solutions. It examines the use of artificial intelligence (AI), machine learning (ML), and deep learning (DL) approaches to improve cancer risk assessment using a Kaggle dataset. The study uses Java-based ML software to create and evaluate multiple predictive models, taking advantage of its powerful libraries and frameworks for processing and analyzing cancer risk indicators. This work analyzes model performance using 10-fold cross-validation, resulting in reliable generalization and accuracy estimates. Several classification techniques, such as Random Forest (RF), logistic regression (LR), decision trees (DT), Naive Bayes (NB), and Multi-layer perceptron (MLP), are used to assess their efficacy in predicting risk levels for various cancer types. To measure classification effectiveness, key performance metrics such as accuracy, precision, recall, and F1 score are produced, in addition to multi-class confusion matrices. The results show that the RF model is the best classifier for classification, with accuracy of 99.85%, F-measure of 99.80%, precision of 99.80%, and sensitivity of 99.90%. These findings demonstrate the model’s ability to effectively estimate cancer risk levels among individuals, allowing for earlier discovery and more effective medical care.

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