Perioperative intravenous lidocaine for gastrointestinal recovery and pain control in elective colorectal surgery: a systematic review and updated meta-analysis of randomized controlled trials

Review Aug 2026

Efficacy and safety of intraperitoneal lidocaine in patients undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized clinical trials.

IP lidocaine provides significant pain relief and reduces opioid consumption following LC compared to placebo, and represents a safe, cost-effective adjunct for multimodal analgesia in LC, particularly for addressing shoulder tip pain.

Sajid Hussain Altaf Hussain, H. Saati, Marya Ahsan et al. · Irish Journal of Medical Sci... · 0 citations

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Review Sep 2026

Procedure-specific effects of intravenous lidocaine in adult spine surgery: a systematic review and meta-analysis of randomized controlled trials.

There is moderate-certainty evidence that perioperative intravenous lidocaine reduces postoperative pain and opioid consumption after adult spine surgery and this benefit appeared procedure-specific, with the greatest benefit after instrumented fusion and complex procedures.

V. Felippe, C. Bersot, G. L. González et al. · Regional anesthesia and pain... · 1 citation

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Meta-analysis Open access Sep 2026

Efficacy and safety of laparoscopic-guided transversus abdominis plane block versus port-site local anesthetic infiltration in laparoscopic cholecystectomy

LTAP block provides superior early postoperative analgesia compared with port-site local anesthetic infiltration after laparoscopic cholecystectomy, with a modest reduction in hospital stay, although evidence for several secondary outcomes remains limited by heterogeneity and inconclusive trial sequential analysis.

J. Javed, M. Qasim, Zaryab Bacha et al. · Medicine · 0 citations

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Review Open access Aug 2026

Current evidence of multimodal anesthesia on postoperative outcomes: A systematic review and Meta-analysis.

MMA shows no clear effect on postoperative pain at 24 h but reduces PONV incidence and opioid consumption, and larger, standardized trials are needed to define optimal MMA regimens and patient selection.

Stefano M. Arigoni, Adina B Heitmann-Frei, Marc von Gernler et al. · Journal of clinical anesthes... · 0 citations

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Review Open access Aug 2026

Effect of Intravenous Magnesium on Postoperative Pain and Analgesic Outcomes in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background: Intravenous magnesium sulfate has been proposed as an adjuvant analgesic in perioperative care; however, its effects on postoperative pain and related analgesic outcomes remain uncertain. Methods: A systematic search of the literature was conducted from 1 January 2015 through 19 January 2026 to identify ran...

L. Tomaszek, W. Mędrzycka-Dąbrowska, S. Lange et al. · Pharmaceuticals · 0 citations

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Review Aug 2026

Intravenous magnesium sulfate for analgesia in spinal surgery: a systematic review and meta-analysis of randomized controlled trials.

Perioperative intravenous magnesium sulfate improves analgesia and reduces opioid consumption in spinal surgery, especially with a bolus-plus-infusion regimen, but it may delay emergence and increase hypotension risk.

Yao Huang, Peng Yuan, Lei Cao et al. · Journal of clinical anesthes... · 0 citations

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