Symposium 4: Vitamins, infectious and chronic disease during adulthood and aging Nutritional influences on epigenetics and age-related disease

Nutrigenomics and Epigenetic Regulation in Cancer Prevention: Molecular Mechanisms, Dietary Bioactives, and Translational Perspectives

Cancer development is influenced not only by genetic alterations but also by epigenetic dysregulation driven by environmental and lifestyle factors, particularly diet. Nutrigenomics investigates how dietary components interact with the genome to influence gene expression, while nutritional epigenetics focuses on diet-i...

Targeting epigenetic checkpoints in autoimmune diseases: Nutritional and lifestyle interventions

Autoimmune diseases are complex disorders arising from interactions among genetic susceptibility, epigenetic regulation, and environmental exposures. Accumulating evidence indicates that DNA methylation, histone modifications, and non-coding RNAs (ncRNAs) may mediate some of the effects of environmental factors on immu...

The Epigenetic Aging–Cancer Continuum: Biomarkers, Metabolism, and Therapy

The epigenetic aging–cancer link, how nutrition and metabolism modify pathways, and the potential of circulating biomarkers for diagnosis, prognosis, prediction, and monitoring are explored.

Lecture Interplay of early-life nutritional programming on obesity, inflammation and epigenetic outcomes

Exercise alone or combined with functional foods in aging and age-related diseases: targeting DNA damage, repair pathways, and genome integrity

Aging is fundamentally associated with the gradual accumulation of DNA damage, which is instrumental in the initiation and advancement of age-associated pathologies, including neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease. Recent studies indicate that lifestyle modifications—especiall...

Epigenetic modifications in type 2 diabetes mellitus.

Type 2 diabetes mellitus (T2DM) develops through the interplay of insulin resistance and progressive beta-cell dysfunction. Beyond genetic predisposition, epigenetic regulation provides a mechanistic link between environmental exposures (e.g., overnutrition, physical inactivity, inflammation) and durable changes in gen...