Visual classifiers are expected to generalize under data shifts, target shifts, and their combinations, yet most existing methods focus on domain invariance while failing to address intra-image predictive sufficiency. We investigate the structural hypothesis that each image contains a sample-adaptive oracle intra-image predictive subset sufficient for label prediction, while the remaining patches form non-essential complementary context that may correlate with the label. The theoretical analysis shows that restricting prediction to this oracle subset preserves the Bayes risk achievable by the full-patch representation while admitting a complexity bound that tightens with the oracle-subset size. Based on this view, we propose PatchGen, a text-free module that learns a sample-dependent soft predictive-subset mask as a task-driven proxy for the unobserved oracle subset mask. Specifically, histopathology visualizations suggest that PatchGen assigns higher scores to tumor-consistent regions than to some frequently co-occurring inflammatory context. Extensive experiments on natural and histopathological image benchmarks spanning all three shift settings show that PatchGen improves average performance over matched-backbone baselines in most evaluated configurations, enhances generalization to unknown classes, and remains competitive with vision-language methods without text supervision.
Deep learning image classifiers achieve strong predictive performance yet remain opaque in how decisions are formed. A model may predict correctly while relying on irrelevant cues, shortcut associations, peripheral structures, or device level artifacts instead of task relevant regions. On large scale datasets this opacity is especially problematic, since inspecting heatmaps one sample at a time cannot scale to thousands of predictions. We propose Relevance Based Model Decision Explainability (ReMoDEx), a framework for systematic, dataset scale assessment of model decision behaviour in image classification. ReMoDEx defines a stepwise pipeline: model inference, target class selection, relevance map generation, heatmap standardisation, similarity based grouping of patterns, cluster level interpretation, and spatial relevance assessment. Local methods GradCAM++, Integrated Gradients, Occlusion Sensitivity, and Layerwise Relevance Propagation are each combined independently with a single global module that summarises an entire set of relevance maps into a few decision strategy clusters, replacing sample by sample inspection with an automatic, scalable summary. To demonstrate ReMoDEx, we applied it to a VGG16 based classifier distinguishing COVID-19, Normal, Lung Opacity, and Viral Pneumonia. The classifier showed stable performance (86.27% test accuracy, 0.9624 test AUC). However, each explainer combined with the global module consistently produced two recurring strategies: central thoracic region decisions and border/corner sensitive decisions, indicating possible shortcut learning that conventional metrics could not reveal. Masked image validation confirmed that model confidence and predicted class changed when central or peripheral regions were occluded. ReMoDEx thus provides a scalable relevance based decision assessment framework and an essential complement to accuracy based evaluation.
Deep learning has shown strong potential in medical image analysis, but most existing methods rely on large-scale annotations and a closed-world assumption that rarely holds in clinical practice. Although Generalized Category Discovery (GCD) has advanced rapidly on natural images, it remains underexplored in medical imaging. To address this issue, we propose MedXplore, a unified framework for reliable and unbiased medical GCD, optimizing from both perceptual and decision levels. Specifically, at the perceptual level, taking a frequency domain perspective, Frequency-SNR Adaptive Attention and Consistency (FAAC) performs learnable full-spectrum filtering and global-local energy contrast activation to not only highlight local abnormal signals relative to the global context, but also provide reliable semantic anchors for patch consistency learning. At the decision level, Adaptive Cosine-Angular Margin (ACAM) adjusts angular margins using semantic difficulty and feature confidence to balance intra-class compactness and inter-class separability. Together, the two modules improve lesion-sensitive representation learning and mitigate old-class bias. Experiments on multiple benchmarks show an average \textbf{8.5\%} gain in \textit{All} accuracy over the strongest competing methods. On Kvasir, MedXplore reduces false-old errors from 14.50\% to 0.80\%, demonstrating strong robustness under severe old-new ambiguity.
Jianwei He, Kailin Lyu, Junhao Dong et al.· 0 citations
AI-generated image detectors generalize poorly when their training and test images originate from different generators or datasets. Despite the rich spatial representations produced by vision foundation models like DINO, existing detectors typically classify images using only the globally aggregated CLS token. We hypothesize that globally aggregating DINO features into a single CLS token obscures spatially distributed generation traces. To test this hypothesis, we introduce PatchHead, a lightweight spatial aggregation head that preserves the two-dimensional organization of DINO patch tokens and integrates evidence across neighboring regions. During training, we freeze the pretrained DINO backbone and optimize only the inserted LoRA adapters, PatchHead, and auxiliary projection head. Across nine cross-dataset benchmarks spanning manually curated and in-the-wild settings, PatchHead ranks first on seven datasets and second on the remaining two. It improves the strongest prior method from 91.6% to 94.6% in average balanced accuracy (+3.0 points) and raises the worst-case accuracy from 82.4% to 89.4% (+6.9 points), while introducing only 8.6% more trainable parameters and 0.08% additional FLOPs. Further qualitative analysis suggests that PatchHead (i) reduces class-conditional domain discrepancy, and (ii) redirects the representation from content-dominated saliency toward spatially distributed authenticity evidence. Together, these observations provide a representation-level account of why spatial patch aggregation transfers more reliably across generators and datasets than a single CLS-based global representation. Our code and models will be made available upon acceptance.
Shengbo Qi, Hongyi Fang, Benjia Zhou et al.· 0 citations
The target representation defines the distribution an image generator must learn, yet it is often treated as an interchangeable interface. This assumption is particularly questionable for continuous masked generators, which combine contextual inference from visible tokens with conditional modeling of each missing token. We study raw pixels, SD-VAE latents and DINOv2 as well as MAE representation-autoencoder features within a unified masked autoregressive rectified-flow model. Under a shared ImageNet training budget, these spaces exhibit distinct optimization and inference regimes. DINOv2 converges fastest in both iterations and computation but benefits strongly from a wider local denoiser and direct context fusion. Pixels optimize substantially more slowly and require a different prediction, masking, and guidance configuration. MAE reconstructs images more faithfully and exhibits clear semantic clustering, yet produces generations substantially worse than DINOv2. The representations also respond differently to classifier-free guidance and occupy distinct precision-recall trade-offs. Together, our results show that compression, reconstruction fidelity, token dimensionality, and visible semantic clustering do not individually predict generative behavior. Instead, target representations redistribute difficulty across contextual modeling, per-token denoising, and inference-time distributional control.
Marcel Plocher, Bernhard Schölkopf, Andreas Geiger et al.· 0 citations
Multiple Instance Learning (MIL) is a standard weakly supervised approach for Whole Slide Image (WSI) classification, where performance hinges on both feature representation and MIL pooling strategies. Recent research has predominantly focused on Transformer-based architectures adapted for WSIs. However, we argue that this trend faces a fundamental limitation: data scarcity. In typical settings, Transformer models yield only marginal gains without access to large-scale datasets—resources that are virtually inaccessible to all but a few well-funded research labs. Motivated by this, we revisit simple, non-attention MIL with unsupervised slide features and analyze temperature-β -controlled log-sum-exp (LSE) pooling. For slides partitioned into N patches, we theoretically show that LSE has a smooth transition at a critical β crit = O (log N ) threshold, interpolating between mean-like aggregation (stable, better generalization but less sensitive) and max-like aggregation (more sensitive but looser generalization bounds). Grounded in this analysis, we introduce Maxsoft—a novel MIL pooling function that enables flexible control over this trade-off, allowing adaptation to specific tasks and datasets. To further tackle real-world deployment challenges such as specimen heterogeneity, we propose PerPatch augmentation—a simple yet effective technique that enhances model robustness
Hossein Jafarinia, Danial Hamdi, A. Alamdar et al.· Neural Information Processin...· 1 citation
Dynamic Ensemble Selection (DES) is an adaptive ensemble learning paradigm that selects a subset of base classifiers specific to each test input, enabling more flexible predictions than static ensemble methods. Although successful in tabular settings, DES remains largely unexplored in robust vision applications. We introduce VisionDES, a novel DES framework for image classification that uses deep model embeddings to estimate classifier competence. VisionDES leverages pre-trained vision transformer models to embed inputs and employs efficient nearest neighbor search to define a local region of competence for each sample. It then dynamically selects and fuses the most reliable models, using a similarity-weighted combination that down-weights less reliable or adversarially-compromised classifiers. VisionDES is extensively evaluated on various benchmarks and under clean conditions, distribution shifts, and strong adversarial attacks. It consistently outperforms static ensembles and existing uncertainty-based DES methods, improving robust accuracy by up to 20% under strong attacks and 2-3% higher accuracy under distribution shifts, with modest inference overhead. VisionDES offers instance-level interpretability by revealing models' contributions to the final decision.
Firuz Juraev, Mohammad Abuhamad, S. El-Sappagh et al.· Proceedings of the 32nd ACM...· 0 citations