Sep 2026· Recenti progressi in medicina· Vol 117 9, pp.
390-395
· 0 citations
Medicine
TL;DR
Cognitive safety is proposed here as a longitudinal property of the clinician-AI-organization sociotechnical system: its capacity to support or improve clinical performance without eroding independent hypothesis generation, uncertainty calibration, reasoned dissent, metacognitive control, and resilient performance when AI is wrong or unavailable.
Abstract
Current evaluation of artificial intelligence (AI) in healthcare remains largely focused on model accuracy, clinical outcomes, efficiency, and the formal availability of human oversight. These dimensions are necessary but insufficient. A system may improve today's decision while, through repeated use, weakening the clinician's ability to recognise tomorrow's error. Cognitive safety is proposed here as a longitudinal property of the clinician-AI-organization sociotechnical system: its capacity to support or improve clinical performance without eroding independent hypothesis generation, uncertainty calibration, reasoned dissent, metacognitive control, and resilient performance when AI is wrong or unavailable. Automation and augmentation should not be treated as ideological alternatives, but as task-sensitive regimes selected according to ambiguity, reversibility, normative content, and the need to preserve skill formation. A Clinical Cognitive Impact Assessment is outlined to make this proposal empirically testable across pre-deployment evaluation and post-implementation monitoring. Keeping a physician formally in the loop is not enough: healthcare systems must preserve over time the cognitive capacities required to understand, challenge, and, when necessary, interrupt that loop.
This article proposes seven questions that clinicians can run through to evaluate any clinical AI tool in the time it takes to read an abstract, alongside a traffic-light schema for matching oversight to risk and a short list of demands clinicians should make of vendors and institutions.
Alaa Abdelqader, M. Alkhateeb, Abdullah Al-Marrawi et al.· Avicenna Journal of Medicine· 0 citations
Artificial intelligence has moved from a research promise to a clinical reality, functioning less as
a replacement for practitioners than as a force multiplier that extends the reach, speed, and
consistency of expert judgment across the care continuum. This review synthesizes the state of the
field as of 2025, organizi...
Lucky Ilodigwe· International Journal of Med...· 1 citation
A fully on-premise clinical agent that couples local operational control with a multi-perspective reliability framework to support selective autonomy is developed and evaluated, supporting a practical framework for institutionally governed clinical agents.
Li Zhang, G. Wölflein, Dyke Ferber et al.· Nature Medicine· 1 citation
Summary Artificial intelligence (AI) affects clinical trials in two distinct but overlapping ways: as the intervention under evaluation and as infrastructure supporting trial design, recruitment, monitoring, endpoint assessment, analysis, and reporting. In this manuscript, we define AI-as-intervention as AI whose outpu...
A. Armoundas, C. Tarabanis, J. Loscalzo· EClinicalMedicine· 0 citations
The model is based on the principles of interpretivist epistemology, construct-validity theory, and human-in-the-loop (HITL) AI principles and redefines AI as an enhancement tool and not an autonomous interpreter, which sets a conceptual background to future empirical verification of AI systems run by humans.
E. Oladunmoye, M. A. Adewusi· WAMDEVIN International Journ...· 0 citations