Association of dopamine transporter gene DAT1 40-bp 3′ UTR VNTR polymorphism (rs28363170) with Psychiatric disorders susceptibility: A study from the Pakistani population
The present study indicated the variant-trait association of DAT1 40 bp 3′ UTR VNTR with psychiatric conditions in the Pakistani population, suggesting disorder-specific and allele-dependent effects of DAT1 variation.
Cognitive disorders (CDs) are among the most disabling components of the clinical picture of schizophrenia spectrum disorders (SSDs) and lead to a pronounced decline in the quality of life, as well as in social and occupational functioning of patients. CDs in patients with SSDs may be primary or secondary, with the l...
N. Shnayder, E. I. Glushchenko, A. Abramenko et al.· Personalized Psychiatry and...· 0 citations
Evidence linking neuregulin 1 (NRG1) polymorphisms with schizophrenia susceptibility and antipsychotic response remains inconsistent. This analytical observational study combined a case–control genetic analysis with prospective longitudinal assessment to evaluate SNP8NRG241930 (NRG1 rs62510682) in relation to schizophr...
A. Khadijah· Natural Resources for Human...· 0 citations
The findings suggest no significant association between the HTR2A rs6313 and ASD susceptibility in the Jordanian population, and emphasize the need for larger, multi-marker studies to account for regional genetic diversity.
Wiam Khalil, Elaf Adel Al-Dalabeeh, M. Zihlif· Drug Metabolism and Personal...· 0 citations
INTRODUCTION
The link between lipid profiles and various neuropsychiatric conditions has been studied; however, few studies have systematically pooled data to examine comparative associations between lipid components and multiple psychiatric conditions. Therefore, the current study aimed to conduct a comparative analys...
A. Hashmi, Z. Agha, R. Taj et al.· Current molecular medicine· 0 citations
Background: Major depressive disorder (MDD) arises from genetic and environmental factors. We evaluated functional variation in methylenetetrahydrofolate reductase (MTHFR), circulating MTHFR protein, and homocysteine (HCY) in Mexican-Mestizo participants. Methods: We analyzed 1507 individuals across four cohorts: a pri...
Miriam Pavelth Casillas-Ávila, C. Toledo-Lozano, L. Á. Montes Almanza et al.· Behavioral Science· 0 citations
Lower peripheral OXTR DNAm was associated with higher PD-related symptomatology and altered extended fear network connectivity, suggesting that peripheral OXTR DNAm may index aspects of clinical and neural heterogeneity in PD.
Hyunjung Kim, C. Pae, M. Bang et al.· Journal of Affective Disorde...· 0 citations
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